D-Ribose

Ribose, primarily occurring as D-ribose, is an organic compound that occurs widely in nature. Ribose is an aldopentose, that is a monosaccharide containing five CARBON atoms that, in its acyclic form, has an aldehyde functional group at one end. Typically, this species exists in the cyclic form, as depicted in the upper right. It was first reported in 1891 by Emil Fischer. It comprises the backbone of RNA, a biopolymer that is the basis of genetic transcription. It is related to deoxyribose, as found in DNA, by the removal of one hydroxy group. Once phosphorylated, ribose can become a subunit of ATP, NADH, and several other compounds that are critical to metabolism.

The IUPAC name of D-Ribose is (3R,4S,5R)-5-(hydroxymethyl)oxolane-2,3,4-triol. With the CAS registry number 50-69-1, it is also named as Ribo-2,3,4,5-tetrahydroxyvaleraldehyde, D-. The product's categories are Fine Chemical & Intermediates; Sugars, Carbohydrates & Glucosides; Basic Sugars (Mono & Oligosaccharides); Biochemistry; Nucleosides, Nucleotides & Related Reagents; Ribose; Riboses and 2'-Deoxyriboses; Carbohydrates & Derivatives; Alphabetical Listings; Flavors and Fragrances; Q-Z; Biochemicals Found in Plants; Metabolic Pathways; Metabolites and Cofactors on the Metabolic Pathways Chart, and the other registry numbers are 58-91-3; 6915-40-8; 93781-19-2. Besides, it is white powder, which should be stored in closed and cool place at 2-8 °C. In addition, its molecular formula is C₅H₁₀O₅ and molecular weight is 150.13.

The other characteristics of this product can be summarized as: (1)EINECS: 200-059-4; (2)ACD/LogP: -1.47; (3)# of Rule of 5 Violations: 0; (4)ACD/LogD (pH 5.5): -1.47; (5)ACD/LogD (pH 7.4): -1.47; (6)ACD/BCF (pH 5.5): 1; (7)ACD/BCF (pH 7.4): 1; (8)ACD/KOC (pH 5.5): 3.77; (9)ACD/KOC (pH 7.4): 3.77; (10)#H bond acceptors: 5; (11)#H bond donors: 4; (12)#Freely Rotating Bonds: 5; (13)Index of Refraction: 1.612; (14)Molar Refractivity: 31.05 cm³; (15)Molar Volume: 89.2 cm³; (16)Surface Tension: 78.7 dyne/cm; (17)Density: 1.681 g/cm³; (18)Flash Point: 180.8 °C; (19)Melting Point: 95 °C; (20)Water Solubility: 1.00E+06 mg/L at 25 °C; (21)Enthalpy of Vaporization: 72.06 kJ/mol; (22)Boiling Point: 375.4 °C at 760 mmHg; (23)Vapour Pressure: 3.6E-07 mmHg at 25 °C.

Preparation of Uses D-Ribose: first, please ferment D-glucose. And then you would obtain this chemical by the separation and purification of the resultant. Additionally, this chemical comprises the backbone of RNA, a biopolymer that is the basis of genetic transcription. It is a useful biochemical reagent, pharmaceutical intermediate used in the pharmaceutical industry. Moreover, it can be used as sweetener and flavoring in the food industry. It also can be used as growth promoting agent of crops and feed additive.

When you are using this chemical, please be cautious about it as the following: it is irritating to eyes and skin. In case of contact with eyes, please rinse immediately with plenty of water and seek medical advice. And you should wear gloves and eye/face protection to avoid contact with skin and eyes.

People can use the following data to convert to the molecule structure.
(1)SMILES: O[C@@H]1[C@H](OC(O)[C@@H]1O)CO
(2)InChI: InChI=1/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5?/m1/s1
(3)InChIKey: HMFHBZSHGGEWLO-SOOFDHNKBV