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DESACETYLCOLCHICINE-d-TARTRATE

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DESACETYLCOLCHICINE-d-TARTRATE

EINECS N/A
CAS No. 49720-72-1 Density N/A
PSA N/A LogP N/A
Solubility N/A Melting Point N/A
Formula C20H23NO5•C4H6O6•H2O Boiling Point N/A
Molecular Weight 525.56 Flash Point N/A
Transport Information N/A Appearance N/A
Safety Poison by parenteral and intraperitoneal routes. Human systemic effects by ingestion: nausea or vomiting, leukopenia and thrombocytopenia. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 49720-72-1 (DESACETYLCOLCHICINE-d-TARTRATE			) Hazard Symbols N/A
Synonyms

N/A

 

DESACETYLCOLCHICINE-d-TARTRATE Chemical Properties

Product Name: Desacetylcolchicine d-tartrate (CAS NO.49720-72-1)


Molecular Formula: C24H29NO11
Molecular Weight: 507.4872g/mol
Mol File: 49720-72-1.mol
Boiling point: 626.6 °C at 760 mmHg
Flash Point: 287 °C
Enthalpy of Vaporization: 92.74 kJ/mol
Vapour Pressure: 1.29E-15 mmHg at 25°C
H-Bond Donor: 5
H-Bond Acceptor: 12
Rotatable Bond Count: 7
Topological Polar Surface Area: 195
Heavy Atom Count: 36
Complexity: 772
Defined Atom StereoCenter Count: 3
Covalently-Bonded Unit Count: 2

DESACETYLCOLCHICINE-d-TARTRATE Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 parenteral 9500ug/kg (9.5mg/kg)   Progress in Medical Chemistry. Vol. 9, Pg. 1, 1973.
human TDLo oral 200ug/kg/7D-I (0.2mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

BLOOD: LEUKOPENIA

BLOOD: THROMBOCYTOPENIA
Cancer Chemotherapy Reports, Part 1. Vol. 56, Pg. 263, 1972.
mouse LD50 intraperitoneal 70520ug/kg (70.52mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse LD50 parenteral 8mg/kg (8mg/kg)   Progress in Medical Chemistry. Vol. 9, Pg. 1, 1973.
rat LD50 parenteral 3mg/kg (3mg/kg)   Progress in Medical Chemistry. Vol. 9, Pg. 1, 1973.

DESACETYLCOLCHICINE-d-TARTRATE Safety Profile

Poison by parenteral and intraperitoneal routes. Human systemic effects by ingestion: nausea or vomiting, leukopenia and thrombocytopenia. When heated to decomposition it emits toxic fumes of NOx.

DESACETYLCOLCHICINE-d-TARTRATE Specification

 Desacetylcolchicine d-tartrate ,its CAS NO. is 49720-72-1,the synonyms is Benzo(a)heptalen-9(5H)-one, 7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-, (S)-, tartrate (1:1) ; Colchicine, deacetyl-, L-tartrate ; Colchicinic acid, O,O',O'',O'''-tetramethyl-, tartrate (6CI) ; TMCA methyl ester d-tartrate, hydrate ; Trimethylcolchicinic acid, methyl ether, L-tartrate .

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