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DEXAMETHASONE VALERATE

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Name

DEXAMETHASONE VALERATE

EINECS 251-669-2
CAS No. 33755-46-3 Density 1.24 g/cm3
PSA 100.90000 LogP 3.63680
Solubility N/A Melting Point N/A
Formula C27H37 F O6 Boiling Point 607.5 °C at 760 mmHg
Molecular Weight 476.586 Flash Point 321.2 °C
Transport Information N/A Appearance N/A
Safety Poison by subcutaneous route. Moderately toxic by skin contact. Experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F. Risk Codes N/A
Molecular Structure Molecular Structure of 33755-46-3 (9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-valerate) Hazard Symbols N/A
Synonyms

Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy-16a-methyl-, 17-valerate (8CI); DV17; Dexamethasone 17-valerate; Dexamethasone valerate

 

DEXAMETHASONE VALERATE Chemical Properties

Product Name: Dexamethasone valerate (CAS NO.33755-46-3)


Molecular Formula: C27H37FO6
Molecular Weight: 476.5774832g/mol
Mol File: 33755-46-3.mol
Einecs: 251-669-2
Boiling point: 598.9 °C at 760 mmHg
Flash Point: 316 °C
Density: 1.24 g/cm3
Surface Tension: 50.8 dyne/cm
Enthalpy of Vaporization: 102.31 kJ/mol
Vapour Pressure: 7.72E-17 mmHg at 25
XLogP3: 3.6
H-Bond Donor: 2
H-Bond Acceptor: 7

DEXAMETHASONE VALERATE Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral > 3gm/kg (3000mg/kg)   Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 8, Pg. 23, 1982.
mouse LD50 skin 1784mg/kg (1784mg/kg)   Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 8, Pg. 23, 1982.
mouse LD50 subcutaneous 238mg/kg (238mg/kg) BEHAVIORAL: MUSCLE WEAKNESS Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 8, Pg. 23, 1982.
rabbit LD50 subcutaneous 100mg/kg (100mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
rat LD50 oral > 3gm/kg (3000mg/kg)   Drugs in Japan Vol. -, Pg. 662, 1990.
rat LD50 subcutaneous 117mg/kg (117mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.

DEXAMETHASONE VALERATE Safety Profile

Poison by subcutaneous route. Moderately toxic by skin contact. Experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F.

DEXAMETHASONE VALERATE Specification

 Dexamethasone valerate ,its CAS NO. is 33755-46-3,the synonyms is 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17-valerate ; Dexamethasonevalerate ; DXMvalerate ; Dexamethasone-17-valerate ; DV 17 ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-17-[(1-oxopentyl)oxy]-, (11β,16α)- ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 17-valerate (8CI) ; 9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-valerate .

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