Basic information
- Name:
Methanamine,N-methyl-, hydrochloride (1:1)
- Superlist Name:
- Dimethylamine hydrochloride
- CAS No.:
506-59-2
- Molecular Structure:

- Formula:
- C2H7N.HCl
- Synonyms:
- Methanamine, N-methyl-, hydrochloride (9CI);Dimethylammonium chloride;
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Specification
The Dimethylamine HCl, with the CAS registry number 506-59-2, is also known as Dimethylammonium chloride. It belongs to the product categories of Amine Salts; Nitrogen Compounds; Organic Building Blocks. Its EINECS registry number is 208-046-5. This chemical's molecular formula is C2H8ClN and molecular weight is 81.54. What's more, both its IUPAC name and systematic name are the same which is called N-Methylmethanamine hydrochloride. This chemical can be prepared by Dimethylamine with Hydrochloric acid.
Physical properties about Dimethylamine HCl are: (1)ACD/LogP: -0.43; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.53; (4)ACD/LogD (pH 7.4): -3.33; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 3.24 Å2; (13)Enthalpy of Vaporization: 26.4 kJ/mol; (14)Boiling Point: 6.1 °C at 760 mmHg; (15)Vapour Pressure: 1520 mmHg at 25 °C.
Uses of Dimethylamine HCl: (1) it is used as catalysator of acetylation analysis, raw materials of pharmaceutical and organic synthesis; (2) it is used to produce other chemicals. For example, it can react with 1-Methyl-pyrrole, Formaldehyde to get Dimethyl-(1-methyl-pyrrol-2-ylmethyl)-amine. The reaction occurs with solvent H2O. The reaction time is 6 hours. The yield is 70 %.

When you are dealing with this chemical, you should be very careful. This chemical is irritating to eyes, respiratory system and skin. If swallowed, it's harmful to health. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. And in case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice.
You can still convert the following datas into molecular structure:
(1) SMILES: Cl.N(C)C
(2) InChI: InChI=1S/C2H7N.ClH/c1-3-2;/h3H,1-2H3;1H
(3) InChIKey: IQDGSYLLQPDQDV-UHFFFAOYSA-N
The toxicity data is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | oral | 1600mg/kg (1600mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 32(6), Pg. 12, 1967. | |
| mouse | LD50 | intraperitoneal | 1570mg/kg (1570mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Japanese Journal of Pharmacology. Vol. 17, Pg. 475, 1967. Link to PubMed |
| mouse | LD50 | intravenous | 1210mg/kg (1210mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 112, Pg. 36, 1957. Link to PubMed | |
| mouse | LD50 | oral | 8100mg/kg (8100mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 32(6), Pg. 12, 1967. | |
| mouse | LD50 | subcutaneous | 2gm/kg (2000mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 112, Pg. 36, 1957. Link to PubMed | |
| rabbit | LD50 | oral | 1600mg/kg (1600mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 32(6), Pg. 12, 1967. | |
| rat | LD50 | oral | 1070mg/kg (1070mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 32(6), Pg. 12, 1967. |
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