LookChem
Product Suppliers Buy offers MSDS
Current position:Home >Hot Product_List > Desonide

Desonide (638-94-8)

Please post your buying leads,so that our qualified suppliers will soon contact you!
* Required Fields
Chemistry

Molecular Structure of Desonide (CAS NO.638-94-8):

Empirical Formula: C24H32O6
Molecular Weight: 416.5073
#H bond acceptors: 6
H bond donors: 2
Freely Rotating Bonds: 4
Polar Surface Area: 71.06Å2
Index of Refraction: 1.598
Molar Refractivity: 109.26 cm3
Molar Volume: 320.1 cm3
Surface Tension: 55.9 dyne/cm
Density: 1.3 g/cm3
Flash Point: 196.9 °C
Enthalpy of Vaporization: 99.64 kJ/mol
Boiling Point: 580.1 °C at 760 mmHg
Vapour Pressure: 7.16E-16 mmHg at 25°C
EINECS: 211-351-6
Product Categories: Chiral Reagents; Intermediates & Fine Chemicals; Pharmaceuticals; Steroids
InChI
InChI=1/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15?,16-,17?,19+,20+,22?,23?,24+/m0/s1
Smiles
O1C(C)(C)O[C@@H]2C[C@@H]3[C@@](C[C@@H](O)[C@H]4[C@@H]3CCC=3[C@@]4(C=CC(C3)=O)C)(C)[C@]12C(=O)CO

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 3710mg/kg (3710mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 111, 1970.
rat LD50 subcutaneous 93mg/kg (93mg/kg)   Toxicology and Applied Pharmacology. Vol. 20, Pg. 522, 1971.

Specification

  Desonide , with CAS number of 638-94-8, can be called (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-Hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-on ; 11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ; 11b,16a,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione Cyclic 16,17-Acetal with Acetone ; 11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone . Desonide (CAS NO.638-94-8) is mainly used to treat atopic dermatitis ,seborrheic dermatitis, and contact dermatitis in both adults and children , it is available as a cream, ointment, lotio.

Desonide Basic information

  • Product Name:

    Desonide

  • CAS No:638-94-8
  • Formula:C24H32O6
  • Molecular Structure:Molecular Structure of (<span class=bigs><a href=/cas-638/638-94-8.html />638-94-8</a></span>) (Desonide)
  • Synonyms:Prenacid;Desilux;Pregna-1,4-diene-3,20-dione,11,21- dihydroxy-16,17-[(1-methylethylidene)bis- (oxy)]-,(11a,16R)-;Topifug;Locapred;Tridesilon;Flusemidon;D 2083;Zotinar;16-alpha-Hydroxyprednisole-16,17-acetonide;D-2083;11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone;Hamiltoderm;Desonida [INN-Spanish];Desonide [USAN:BAN:INN];Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)-;Apolar;Otic Tridesilon;Steroderm;Prednisolone-16,17-acetonide, 16-alpha-hydroxy-;DesOwen;Prednacinolone;Tridesonit;Sterax;Reticus;Desonidum [INN-Latin];Budesonide acetonide;
Other Products