Desonide

Molecular Structure of Desonide (CAS NO.638-94-8):

Empirical Formula: C₂₄H₃₂O₆
Molecular Weight: 416.5073
#H bond acceptors: 6
H bond donors: 2
Freely Rotating Bonds: 4
Polar Surface Area: 71.06Ų
Index of Refraction: 1.598
Molar Refractivity: 109.26 cm³
Molar Volume: 320.1 cm³
Surface Tension: 55.9 dyne/cm
Density: 1.3 g/cm³
Flash Point: 196.9 °C
Enthalpy of Vaporization: 99.64 kJ/mol
Boiling Point: 580.1 °C at 760 mmHg
Vapour Pressure: 7.16E-16 mmHg at 25°C
EINECS: 211-351-6
Product Categories: Chiral Reagents; Intermediates & Fine Chemicals; Pharmaceuticals; Steroids
InChI
InChI=1/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15?,16-,17?,19+,20+,22?,23?,24+/m0/s1
Smiles
O1C(C)(C)O[C@@H]2C[C@@H]3[C@@](C[C@@H](O)[C@H]4[C@@H]3CCC=3[C@@]4(C=CC(C3)=O)C)(C)[C@]12C(=O)CO

  Desonide , with CAS number of 638-94-8, can be called (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-Hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-on ; 11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ; 11b,16a,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione Cyclic 16,17-Acetal with Acetone ; 11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone . Desonide (CAS NO.638-94-8) is mainly used to treat atopic dermatitis ,seborrheic dermatitis, and contact dermatitis in both adults and children , it is available as a cream, ointment, lotio.