The Acetamide,N-[4-(acetyloxy)phenyl]-, with the CAS registry number 2623-33-8, is also known as N,O-diacetyl-4-aminophenol and 4-(Acetylamino)phenyl acetate. It belongs to the product category of Impurities. Its EINECS registry number is 220-077-6. This chemical's molecular formula is C₁₀H₁₁NO₃ and molecular weight is 193.2. What's more, both its IUPAC name and systematic name are the same which is called 4-(Acetylamino)phenyl acetate.

Physical properties about this chemical are: (1).ACD/LogP: 0.60; (2)#of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.6; (4)ACD/LogD (pH 7.4): 0.6; (5)ACD/BCF (pH 5.5): 1.68; (6)ACD/BCF (pH 7.4): 1.68; (7)ACD/KOC (pH 5.5): 50.48; (8)ACD/KOC (pH 7.4): 50.48; (9)#H bond acceptors: 4; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 46.61 Å²; (13)Index of Refraction: 1.561; (14)Molar Refractivity: 51.86 cm³; (15)Molar Volume: 160.1 cm³; (16)Polarizability: 20.56×10^-24cm³; (17)Surface Tension: 44 dyne/cm; (18)Density: 1.206 g/cm³; (19)Flash Point: 181.4 °C; (20)Enthalpy of Vaporization: 62.4 kJ/mol; (21)Boiling Point: 376.4 °C at 760 mmHg; (22)Vapour Pressure: 7.27E-06 mmHg at 25 °C.

Preparation of Acetamide,N-[4-(acetyloxy)phenyl]: this chemical can be prepared by Acetic acid anhydride and 4-Amino-phenol.



This reaction needs reagent Et₃N and solvent CH₂Cl₂ at temperature of 0 °C. The reaction time is 4 hours. The yield is 87 %.

Uses of Acetamide,N-[4-(acetyloxy)phenyl]: it is used to produce other chemicals. For example, it is used to produce 1-(5-Acetylamino-2-hydroxy-phenyl)-ethanone.
 

The reaction occurs with reagent AlCl₃ and other condition of heating.

When you are dealing with this chemical, you should be very careful. This chemical is irritating to eyes, respiratory system and skin. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. And in case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(Oc1ccc(cc1)NC(=O)C)C
(2) InChI: InChI=1/C10H11NO3/c1-7(12)11-9-3-5-10(6-4-9)14-8(2)13/h3-6H,1-2H3,(H,11,12)
(3) InChIKey: UJAOSPFULOFZRR-UHFFFAOYAD