Diallyldisulfide Synthetic route
Conditions
| Conditions | Yield |
|---|
| With nanophase manganese (VII) oxide coated clay (NM7O coated clay) In toluene at 40℃; for 3h; | 99% |
| With water; dihydrogen peroxide In various solvent(s) at 20℃; for 0.166667h; Oxidation; Dimerization; | 94% |
| CoCl2 In acetonitrile Ambient temperature; | 90% |
Conditions| Conditions | Yield |
|---|
| With 1,2-bis(5-methylisoxazol-3-yl)hydrazine; sodium carbonate; thiourea In water; acetonitrile at 80℃; for 2h; | 95% |
| With sodium sulfide trihydrate; hexachloroethane at 20℃; for 0.833333h; Reagent/catalyst; | 93% |
| With Sodium thiosulfate pentahydrate; water; dimethyl sulfoxide at 50 - 60℃; for 3.5h; pH=< 3; | 91% |
Conditions| Conditions | Yield |
|---|
| With lithium sulfide; sulfur; cetyl trimethyl ammonium bromide In chloroform; water for 1h; Ambient temperature; | 95% |
| With 1,2-bis(5-methylisoxazol-3-yl)hydrazine; sodium carbonate; thiourea In water; acetonitrile at 80℃; for 3h; | 92% |
| With sodium sulfide trihydrate; hexachloroethane at 20℃; for 1h; Reagent/catalyst; | 91% |
Conditions| Conditions | Yield |
|---|
| With tetrachloromethane; water; triethylamine In glycerol at 50℃; for 12h; | 94% |
| With sodium carbonate In water; acetonitrile at 80℃; for 3h; | 92% |
Conditions| Conditions | Yield |
|---|
| With sodium carbonate; sulfur; thiourea In water at 70℃; for 5h; Green chemistry; | 90% |
Conditions| Conditions | Yield |
|---|
| With sodium carbonate In water; acetonitrile at 80℃; for 3h; | 87% |
Conditions| Conditions | Yield |
|---|
| With samarium; titanium tetrachloride In tetrahydrofuran at 0℃; | 82% |
Conditions| Conditions | Yield |
|---|
Stage #1: S-allyl ethanethioate With hydrogenchloride; water In methanol at 50℃;
Stage #2: With iodine In methanol; water at 0℃; for 0.75h; | 82% |
Conditions| Conditions | Yield |
|---|
| With hydrogen sulfide; dimethyl sulfoxide at 50℃; for 3h; | 76.3% |
Conditions| Conditions | Yield |
|---|
| With hydrogen sulfide In dimethyl sulfoxide at 40℃; for 3h; | A 11%
B 50.8% |
Diallyldisulfide Chemical Properties
Molecular Structure of Allyl disulfide (CAS NO.2179-57-9):
.gif)
IUPAC Name: 3-(Prop-2-enyldisulfanyl)prop-1-ene
Molecular Formula: C6H10S2
Molecular Weight: 146.26
XLogP3-AA: 2.2
EINECS: 218-548-6
FEMA: 2028
storage temp.: 2-8 °C
Index of Refraction: 1.534
Molar Refractivity: 45.29 cm3
Molar Volume: 145.7 cm3
Surface Tension: 33.3 dyne/cm
Density: 1.003 g/cm3
Flash Point: 42.4 °C
Enthalpy of Vaporization: 40.4 kJ/mol
Boiling Point: 185 °C at 760 mmHg
Vapour Pressure: 0.976 mmHg at 25 °C
Product Categories: sulfide Flavor
Appearance: clear yellow liquid
Classification Code: Anticarcinogenic agents; Antihypertensive agents; Antimutagenic agents; Antineoplastic agents; Antispermatogenic Agents; Cardiovascular Agents; Contraceptive Agents; Contraceptive Agents, Female; Mutation data; Noxae; Protective Agents; Reproductive Control Agents; Spermatocidal agents
Diallyldisulfide Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
| rabbit | LD50 | skin | 3600mg/kg (3600mg/kg) | | Food and Chemical Toxicology. Vol. 26, Pg. 297, 1988. |
| rat | LD50 | oral | 260mg/kg (260mg/kg) | | Food and Chemical Toxicology. Vol. 26, Pg. 297, 1988. |
Diallyldisulfide Consensus Reports
Reported in EPA TSCA Inventory.
Diallyldisulfide Safety Profile
Safety Information of Allyl disulfide (CAS NO.2179-57-9):
Hazard Codes: 
Xn,
Xi
Risk Statements: 22-36/37/38-10
R10:Flammable.
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39-37/39-16-36
S16:Keep away from sources of ignition.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S37/39:Wear suitable gloves and eye/face protection.
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
RTECS: BB1000000
F: 13
HazardClass: 6.1
PackingGroup: II
Poison by ingestion. Moderately toxic by skin contact. When heated to decomposition it emits toxic vapors of SOx.
Diallyldisulfide Specification
Allyl disulfide (CAS NO.2179-57-9), its Synonyms are 2-Propenyl disulfide ; 2-Propenyl disulphide ; 4,5-Dithia-1,7-octadiene ; Di(2-propenyl) disulfide ; Diallyl disulfide ; Diallyl disulphide ; Disulfide, di-2-propenyl ; Disulfide, di-2-propen-1-yl .
Xn,
Xi
