Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
Dichloromonofluoromethane |
EINECS | 200-869-8 |
CAS No. | 75-43-4 | Density | 1.397 g/cm3 |
PSA | 0.00000 | LogP | 1.71710 |
Solubility | Slightly soluble in water | Melting Point |
-135 °C |
Formula | CHCl2F | Boiling Point | 8.9 °C at 760 mmHg |
Molecular Weight | 102.923 | Flash Point | 130-132°C/3mm |
Transport Information | N/A | Appearance | COLOURLESS GAS OR COMPRESSED LIQUEFIED GAS, WITH CHARACTERISTIC ODOUR. |
Safety | 59 | Risk Codes | 59 |
Molecular Structure | Hazard Symbols | N | |
Synonyms |
AF 22;AF22 (fluorocarbon);Algofrene Type 5;Arcton 7;CFC 21;Dichlorofluoromethane;Dichloromonofluoromethane;F 21;F 21 (fluorocarbon);FC 21;Fluorocarbon-21;Fluorodichloromethane;Freon 21;Genetron 21;HCFC 21;Monofluorodichloromethane;R 21;R 21 (refrigerant); |
Article Data | 57 |
1,1-dichloroperfluoro-2-butanone
A
Dichlorofluoromethane
B
sodium formate
C
sodium pentafluoropropionate
Conditions | Yield |
---|---|
With sodium hydroxide In water Product distribution; | A 33.5% B n/a C 84.5% |
Conditions | Yield |
---|---|
With N,N,N,N,N,N-hexamethylphosphoric triamide In N,N-dimethyl-formamide at 20℃; for 0.5h; | 20% |
With ruthenium(II) bis(triphenylphosphine) dichloride; hydrogen In ethanol; toluene at 25℃; for 12h; Product distribution; also carbon tetrachloride; also in the presence of RuCl2(dppe)2 or RuHCl(PPh3)2; other solvents; var. time and temp.; | |
titanium pH=7; Kinetics; | |
With formate; titanium(IV) oxide In various solvent(s) at 23℃; for 1h; pH=5.9; Kinetics; Further Variations:; pH-values; Irradiation; |
Conditions | Yield |
---|---|
With uranium hexafluoride | |
With hydrogen fluoride; lithium fluoride at 0℃; |
Conditions | Yield |
---|---|
With antimonypentachloride; antimony(III) fluoride unter Druck; | |
With hydrogen fluoride; antimonypentachloride; antimony(III) chloride | |
With hydrogen fluoride; titanium(IV) fluoride at 127℃; |
dichloromethane
A
Difluoromethane
B
R32
C
Chlorodifluoromethane
D
Dichlorofluoromethane
E
Dichlorodifluoromethane
F
trichlorofluoromethane
Conditions | Yield |
---|---|
With xenon difluoride for 48h; Ambient temperature; other halogenocarbons; var. reaction time; |
Conditions | Yield |
---|---|
zinc aluminate at 300℃; Product distribution; other temperature; |
Conditions | Yield |
---|---|
With antimony tetrachloride fluoride at 100℃; Kinetics; Product distribution; kinetic behaviour of different fluorinated antimony compound in fluorination (SbCl4F, SbCl5 + SbF3Cl2, SbCl5 + SbF5, SbCl5 + SbF3) at different reaction times; | |
With antimony tetrachloride fluoride at 100℃; under 7600 Torr; Kinetics; Product distribution; Equilibrium constant; kinetic at three different temperatures (85, 100, 115 deg C) and at different pressures ( 7.3, 8.0, 10.0, 10.5, 13.0, 13.8 atm); | |
With hydrogen fluoride; antimonypentachloride at 70 - 90℃; under 10746.4 - 10953.3 Torr; Product distribution / selectivity; Heating / reflux; |
(dichloro-fluoro-methyl)-tris-dimethylamino-phosphonium; chloride
A
Dichlorofluoromethane
B
trichlorofluoromethane
C
bromodichlorofluoromethane
D
dibromochlorofluoromethane
Conditions | Yield |
---|---|
With potassium fluoride; bromine In various solvent(s) | A 25 % Spectr. B 15 % Spectr. C 42 % Spectr. D 5 % Spectr. |
dichloromethane
A
Difluoromethane
B
R32
C
Chlorodifluoromethane
D
Dichlorofluoromethane
E
Dichlorodifluoromethane
Conditions | Yield |
---|---|
With osmium pentafluoride oxide Product distribution; other transition-metal oxide fluorides; |
1,1,3,3-tetrachloro-1,3-difluoro-2-propanone
acetone
A
Dichlorofluoromethane
B
HCFC-141b
C
trichlorofluoromethane
D
1-chloro-1-fluoroethane
E
1,1-Dichloroethylene
F
CFC-112a
Conditions | Yield |
---|---|
With propene; sulphur hexafluoride for 0.5h; Rate constant; Ambient temperature; Irradiation; also with acetone-d6; |
The Dichlorofluoromethane is an organic compound with the formula CHCl2F. The IUPAC name of this chemical is dichloro(fluoro)methane. With the CAS registry number 75-43-4, it is also named as methane, dichlorofluoro-. The product's categories are Refrigerants; Organics. Besides, it should be stored in a cool and ventilated place. It is used as a refrigerant.
Physical properties about Dichlorofluoromethane are: (1)ACD/LogP: 1.40; (2)ACD/LogD (pH 5.5): 1.4; (3)ACD/LogD (pH 7.4): 1.4; (4)ACD/BCF (pH 5.5): 6.83; (5)ACD/BCF (pH 7.4): 6.83; (6)ACD/KOC (pH 5.5): 137.75; (7)ACD/KOC (pH 7.4): 137.75; (8)Index of Refraction: 1.366; (9)Molar Refractivity: 16.5 cm3; (10)Molar Volume: 73.6 cm3; (11)Polarizability: 6.54×10-24cm3; (12)Surface Tension: 19.9 dyne/cm; (13)Density: 1.397 g/cm3; (14)Enthalpy of Vaporization: 24.65 kJ/mol; (15)Boiling Point: 8.9 °C at 760 mmHg; (16)Vapour Pressure: 1340 mmHg at 25°C.
Preparation: this chemical can be prepared by trichloro-fluoro-methane. This reaction will need reagent HMPT and solvent dimethylformamide. The reaction time is 30 min with reaction temperature of 20 °C. The yield is about 20%.
Uses of Dichlorofluoromethane: it can be used to produce 7-chlor-7-fluor-1-methylbicyclo[4.1.0]heptan . It will need reagent 55percent KOH, 18-crown-6 with reaction time of 1 hour. The yield is about 80%.
You can still convert the following datas into molecular structure:
(1)SMILES: ClC(Cl)F
(2)InChI: InChI=1/CHCl2F/c2-1(3)4/h1H
(3)InChIKey: UMNKXPULIDJLSU-UHFFFAOYAU
(4)Std. InChI: InChI=1S/CHCl2F/c2-1(3)4/h1H
(5)Std. InChIKey: UMNKXPULIDJLSU-UHFFFAOYSA-N
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LCLo | inhalation | 10pph/1H (100000ppm) | Fluorine Chemistry Reviews. Vol. 1, Pg. 197, 1967. | |
mouse | LC50 | inhalation | > 800gm/m3/2H (800000mg/m3) | BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 20(11), Pg. 38, 1976. |
rat | LC50 | inhalation | 49900ppm/4H (49900ppm) | "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 5, Pg. 187, 1986. |