Reported in EPA TSCA Inventory.

The CAS registry number of Diethyl fumarate is 623-91-6. With the EINECS registry number 210-819-7, its IUPAC name is diethyl (E)-but-2-enedioate. In addition, the molecular formula is C₈H₁₂O₄. What's more, it is a colourless liquid and incompatible with strong oxidizing agents, acids, bases, reducing agents. Besides, it is used as a intermediate and solvent in organic synthesis.

Physical properties about this chemical are: (1)ACD/LogP: 1.68; (2)ACD/LogD (pH 5.5): 1.68; (3)ACD/LogD (pH 7.4): 1.68; (4)ACD/BCF (pH 5.5): 11.2; (5)ACD/BCF (pH 7.4): 11.2; (6)ACD/KOC (pH 5.5): 196.12; (7)ACD/KOC (pH 7.4): 196.12; (8)#H bond acceptors: 4; (9)#Freely Rotating Bonds: 6; (10)Polar Surface Area: 52.6 Å²; (11)Index of Refraction: 1.442; (12)Molar Refractivity: 42.71 cm³; (13)Molar Volume: 161.1 cm³; (14)Polarizability: 16.93 ×10^-24cm³; (15)Surface Tension: 33.2 dyne/cm; (16)Density: 1.068 g/cm³; (17)Flash Point: 93.3 °C; (18)Enthalpy of Vaporization: 45.03 kJ/mol; (19)Boiling Point: 214 °C at 760 mmHg; (20)Vapour Pressure: 0.159 mmHg at 25°C.

Preparation of Diethyl fumarate: it can be prepared by bromo-succinic acid diethyl ester. This reaction will need reagent 1-(trimethylsilyl)-2-pyrrolidinone. The yield is about 58% at reaction temperature of 150-155 °C.

Uses of Diethyl fumarate: it can react with butyraldehyde to get butyryl-succinic acid diethyl ester. This reaction will need reagents di-tert-butyl hyponitrite and tert-dodecanethiol, and solvent dioxane. The reaction time is 3.5 hours at reaction temperature of 60 °C. The yield is about 96%.

When you are using this chemical, please be cautious about it as the following:
This chemical irritates skin and eyes and is harmful if swallowed. During using it, do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer).

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(OCC)\C=C\C(=O)OCC
(2)Std. InChI: InChI=1S/C8H12O4/c1-3-11-7(9)5-6-8(10)12-4-2/h5-6H,3-4H2,1-2H3/b6-5+
(3)Std. InChIKey: IEPRKVQEAMIZSS-AATRIKPKSA-N

The toxicity data is as follows: