Basic information
- Name:
Dimebolin
- CAS No.:
3613-73-8
- Molecular Structure:
- Formula:
- C21H25N3
- Molecular Weight:
- 319.44
- Deleted CAS:
- 12687-54-6|20684-30-4
- Synonyms:
- 1H-Pyrido[4,3-b]indole,2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]- (8CI);2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-1H-pyrido[4,3-b]indole;Dimeboline;Dimebon;Dimebone;Latrepirdine;Preparation 84;
- Density:
- 1.13 g/cm3
- Boiling Point:
- 505.7 °C at 760 mmHg
- Flash Point:
- 259.7 °C
Famous Chemical Enterprises
-
Livzon -
Total -
Shell -
Dupont -
Exxonmobil -
Akzonobel -
Basf -
Bayer -
BP
Please post your buying leads,so that our qualified suppliers will soon
contact you!
*Required Fields
Chemistry
Molecular structure of Dimebolin (CAS NO.3613-73-8) is:
Product Name: Dimebolin
CAS Registry Number: 3613-73-8
IUPAC Name: 2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole
Molecular Weight: 319.4433 [g/mol]
Molecular Formula: C21H25N3
XLogP3-AA: 3.5
H-Bond Donor: 0
H-Bond Acceptor: 2
Surface Tension: 41.5 dyne/cm
Density: 1.13 g/cm3
Flash Point: 259.7 °C
Enthalpy of Vaporization: 77.55 kJ/mol
Boiling Point: 505.7 °C at 760 mmHg
Vapour Pressure: 2.37E-10 mmHg at 25 °C
Classification Code: Reproductive Effect
Uses
Dimebolin (CAS NO.3613-73-8) has been shown to inhibit brain cell death in preclinical studies of Alzheimer's disease and Huntington's disease, making it a potential treatment for these and other neurodegenerative diseases. Also it may have cognition-enhancing effects in healthy individuals.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 178mg/kg (178mg/kg) | Russian Pharmacology and Toxicology Vol. 31, Pg. 105, 1968. | |
| mouse | LDLo | oral | 356mg/kg (356mg/kg) | Farmakologiya i Toksikologiya Vol. 46(5), Pg. 90, 1983. |
Safety Profile
Poison by ingestion and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx.
Specification
Dimebolin , its cas register number is 3613-73-8. It also can be called 2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-1H-pyrido[4,3-b]indole ; Dimeboline ; Dimebon ; Latrepirdine ; 1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)ethyl)- .It is an antihistamine drug and is an orally-active small molecule compound.