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Basic information

  • Name:
  • 1-Propanol,2-[(diethylamino)methyl]-2-methyl-, 1-(4-aminobenzoate)

  • Superlist Name:
  • Dimethocaine
  • CAS No.:
  • 94-15-5

  • Molecular Structure:
  • Formula:
  • C16H26N2O2
  • Molecular Weight:
  • 278.44
  • Synonyms:
  • 1-Propanol,3-(diethylamino)-2,2-dimethyl-, 4-aminobenzoate (ester) (9CI);1-Propanol, 3-(diethylamino)-2,2-dimethyl-,p-amino benzoate (6CI,7CI);1-Propanol, 3-(diethylamino)-2,2-dimethyl-,p-aminobenzoate (ester) (8CI);Dimethocaine;Larocaine;NSC 68927;
  • Density:
  • 1.035 g/cm3
  • Boiling Point:
  • 403.5 °C at 760 mmHg
  • Flash Point:
  • 197.8 °C

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Chemistry

Molecular Formula of Dimethocaine (CAS NO.94-15-5): C16H26N2O2 
Molecular Weight: 278.39 g/mol
Index of Refraction: 1.529
Density: 1.258 g/cm3
Flash Point: 197.8 °C
Enthalpy of Vaporization: 65.48 kJ/mol
Boiling Point: 403.5 °C at 760 mmHg
Vapour Pressure: 1.01E-06 mmHg at 25 °C
Structure of Dimethocaine (CAS NO.94-15-5):
                
IUPAC name: 3-Diethylamino-2,2-dimethylpropyl-4-aminobenzoate

Uses

 Dimethocaine (CAS NO.94-15-5) is a local anesthetic with stimulant properties nearly as potent as cocaine.

Toxicity Data With Reference

1.    

scu-mus LDLo:380 mg/kg

    AEPPAE    Naunyn-Schmiedebergs Archiv fuer Experimentelle Pathologie und Pharmakologie. 168 (1932),447.
2.    

ivn-mus LDLo:40 mg/kg

    PHREA7    Physiological Reviews. 12 (1932),190.
3.    

scu-rbt LDLo:150 mg/kg

    PHREA7    Physiological Reviews. 12 (1932),190.
4.    

ivn-rbt LDLo:150 mg/kg

    PHREA7    Physiological Reviews. 12 (1932),190.
5.    

scu-gpg LDLo:200 mg/kg

    PHREA7    Physiological Reviews. 12 (1932),190.
6.    

par-frg LDLo:200 mg/kg

    AEPPAE    Naunyn-Schmiedebergs Archiv fuer Experimentelle Pathologie und Pharmakologie. 168 (1932),447.

Safety Profile

Poison by subcutaneous, intravenous, and parenteral routes. When heated to decomposition it emits toxic fumes of NOx.

Specification

 Dimethocaine , its cas register number is 94-15-5. It also known as larocaine, (3-Diethylamino-2,2-dimethyl)propyl 4-aminobenzoat ;1-Propanol, 3-(diethylamino)-2,2-dimethyl-, p-aminobenzoate ; and 4-Aminobenzoesaeure-3-diethylamino-2,2-dimethylproplylester .

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