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Direct Blue 14

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Name

Direct Blue 14

EINECS 200-786-7
CAS No. 72-57-1 Density 1.007 g/mL at 20 °C
PSA 404.26000 LogP 10.78520
Solubility water: 10 g/L (25 °C) Melting Point >300 °C(lit.)
Formula C34H24N6Na4O14S4 Boiling Point N/A
Molecular Weight 960.819 Flash Point N/A
Transport Information N/A Appearance blueish grey powder
Safety 53-45-36/37/39-36-26 Risk Codes 45-41-37/38-36/37/38-22
Molecular Structure Molecular Structure of 72-57-1 (Direct Blue 14) Hazard Symbols ToxicT,IrritantXi
Synonyms

2,7-Naphthalenedisulfonicacid,3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxy-,tetrasodium salt (9CI);C.I. Direct Blue 14, tetrasodium salt (8CI);DiphenylBlue (6CI);Amanil Sky Blue R;Bencidal Blue 3B;Benzamine blue;Benzanil Blue3BN;Benzo Blue 3BS;Benzo blue;Blue 3B;Blue EMB;Brasilamina Blue 3B;C.I.23850;Chloramine Blue 3B;Chrome Leather Blue 3B;Congoblue;Cresotine Blue 3B;Diamine Blue 3B;Diamineblue;Diaphtamine Blue TH;Diazine Blue 3B;Diazol Blue 3B;Diphenyl Blue 3B;Direct Blue3B;Hispamin Blue 3BX;Naphthylamine blue;Niagara Blue;Paramine Blue 3B;Pontamine Blue 3BX;Sodiumditolyldisazobis-8-amino-1-naphthol-3,6-disulfonate;Trypan (Congo) Blue;Trypan Blue BPC;Trypan blue;Trypane blue;

 

Direct Blue 14 Chemical Properties

Product Name: C.I. Direct blue 14, tetrasodium salt (CAS NO.72-57-1)


Molecular Formula: C34H24N6Na4O14S4
Molecular Weight: 960.81g/mol
Mol File: 72-57-1.mol
Einecs: 200-786-7
Melting Point: 280 ºC
Storage Temperature: Store at RT.
Density: 1.007 g/mL at 20 °C
Water Solubility: 10 g/L (25 ºC)
Stability: Stable. Incompatible with strong oxidizing agents
Enthalpy of Vaporization:
XLogP3-AA:
H-Bond Donor: 4
H-Bond Acceptor: 20
Product Categories: Dyes and Pigments; Organics; Hematopoietic Stem Cell In Vivo/In Vitro TrackingReagents and Supplements; Stains, Dyes and IndicatorsStains and Dyes; Cell Culture;Cell Viability and Proliferation; Hematopoietic Stem Cell Biology; In Vivo/In Vitro Tracking of Stem CellsStem Cell Biology; Stains&Dyes, A to; Stem Cell Biology; T-U-V

Direct Blue 14 Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo intraperitoneal 250mg/kg (250mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934.
guinea pig LDLo subcutaneous 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934.
mouse LD50 intravenous 328mg/kg (328mg/kg)   Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972.
mouse LD50 subcutaneous 267mg/kg (267mg/kg)   Naunyn-Schmiedebergs Archiv fuer Pharmakologie. Vol. 267, Pg. 31, 1970.
mouse LDLo intraperitoneal 350mg/kg (350mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934.
rabbit LDLo intraperitoneal 400mg/kg (400mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934.
rabbit LDLo intravenous 100mg/kg (100mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934.
rat LD50 oral 6200mg/kg (6200mg/kg)   Office of Toxic Substances Report. Vol. OTS,
rat LDLo intraperitoneal 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934.
rat LDLo intravenous 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934.
rat LDLo subcutaneous 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934.

Direct Blue 14 Consensus Reports

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 8 , 1975,p. 267.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.

Direct Blue 14 Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by intraperitoneal, intravenous, and subcutaneous routes. Experimental teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx, Na2O, and SOx.
Safety Information of C.I. Direct blue 14, tetrasodium salt (CAS NO.72-57-1):
Hazard Codes: T,Xi
Risk Statements: 45-41-37/38-36/37/38-22 
22:  Harmful if swallowed
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
41:  Risk of serious damage to eyes 
45:  May cause cancer
Safety Statements: 53-45-36/37/39-36-26
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing  
37:  Wear suitable gloves  
39:  Wear eye/face protection 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53:  Avoid exposure - obtain special instruction before use

Direct Blue 14 Specification

 C.I. Direct blue 14, tetrasodium salt ,its CAS NO. is 72-57-1,the synonyms is 2,7-Naphthalenedisulfonicacid,3,3'-((3,3'-dimethyl-4,4'-biphenylylene)bis(azo ; 2,7-Naphthalenedisulfonicacid,3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'- ; 2,7-Naphthalenedisulfonicacid,3,3'-[[3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl]bis(azo)]bis(5-amino-4-hydroxy-,tetrasodiumsalt ; Amanilskybluer ; Amidineblue4b ; Azidinblau3b ; Azidineblue3b ; Azurrodiretto3b .

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