Basic information
- Name:
Domperidone maleate
- CAS No.:
99497-03-7
- Molecular Structure:
- Formula:
- C22H24ClN5O2.C4H4O4
- Molecular Weight:
- 541.98
- Synonyms:
- 5-chloro-1-[1-[3-(2-oxo-3H-benzoimidazol-1-yl)propyl]-4-piperidyl]-3H-benzoimidazol-2-one;R 33,812;but-2-enedioic acid; 5-chloro-1-[1-[3-(2-oxo-3H-benzoimidazol-1-yl)propyl]-4-piperidyl]-3H-benzoimidazol-2-one;KW-5338;
- Melting Point:
- 236 - 239 °C
- Boiling Point:
- 778.5 °C at 760 mmHg
- Flash Point:
- 424.7 °C
Famous Chemical Enterprises
-
Livzon -
Total -
Shell -
Dupont -
Exxonmobil -
Akzonobel -
Basf -
Bayer -
BP
Please post your buying leads,so that our qualified suppliers will soon
contact you!
*Required Fields
Chemistry
IUPAC Name:5-Chloro-1-[1-[3-(2-oxo-1,3-dihydrobenzoimidazol-1-yl)propyl]-4-piperidyl]-1,3-dihydrobenzoimidazol-2-one maleate
Molecular Formula:C22H24ClN5O2.C4H4O4
Molecular Weight:541.99 g/mol
Melting Point:236 - 239 °C
Appearance: white powder
Uses
Domperidone maleate (CAS NO.99497-03-7) is a dopamine antagonist used as an antiemetic for the short term treatment of nausea and vomiting of various etiologies.
Toxicity Data With Reference
Toxicity: ORL-RAT LD50 5243 mg kg-1, IPR-RAT LD50 61 mg kg-1, ORL-MUS LD50 > 8000 mg kg-1 .
Analytical Methods
Domperidone maleate(99497-03-7) was determined by several methods including colorimetric methods, spectrophotometric methods, high-performance thin-layer chromatography, high-performance liquid chromatography and titrimetric methods.