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Basic information

  • Name:
  • Ethyleneglycol diethyl ether

  • Superlist Name:
  • 1,2-Diethoxyethane
  • CAS No.:
  • 629-14-1

  • Molecular Structure:
  • Formula:
  • C6H14O2
  • Molecular Weight:
  • 118.20
  • Synonyms:
  • 1,2-Diethoxyethane;2-Ethoxyethyl ethyl ether;3,6-Dioxaoctane;Ethane, 1,2-diethoxy-;Diethyl cellosolve;Glycol diethyl ether;Hisolve EME;
  • EINECS:
  • 211-076-1
  • Density:
  • 0.842 g/cm3
  • Melting Point:
  • -74 °C
  • Boiling Point:
  • 119.4 °C at 760 mmHg
  • Flash Point:
  • 20.6 °C
  • Solubility:
  • slightly soluble in water
  • Appearance:
  • Clear colorless liquid
  • Hazard Symbols:
  • IrritantXi
  • Risk Codes:
  • 10-37/38-41
  • Safety Description:
  • 16-26-36 Details
  • Transport Information:
  • UN 1153

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Chemistry


IUPAC Name: 1,2-Diethoxyethane
CAS NO:629-14-1
Molecular Formula:C6H14O2
Molecular Weight:118.174160 g/mol
EINECS: 211-076-1
Index of Refraction: 1.391
Surface Tension: 23.8 dyne/cm
Density: 0.842 g/cm3
Flash Point: 20.6 °C
Enthalpy of Vaporization: 36.28 kJ/mol
Boiling Point: 119.4 °C at 760 mmHg
Vapour Pressure: 19.1 mmHg at 25 °C
Melting Point: -74 °C
Storage temp: Flammables area
Water Solubility: Slightly soluble
Appearance: a clear colorless liquid with a faint ether-like odor.
Synonyms of Ethylene glycol diethyl ether (CAS NO.629-14-1): 1,2-Ethanediol, diethyl ether ; 2-Ethoxyethyl ethyl ether ; Diethyl cellosolve ; Ethane, 1,2-diethoxy-

Uses

 Ethylene glycol diethyl ether (CAS NO.629-14-1) is used as solvents of nitrocellulose, rubber, resin,etc, as well as the reaction medium in organic synthesis.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 2440mg/kg (2440mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

GASTROINTESTINAL: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
rat LCLo inhalation 8000ppm/4H (8000ppm)   Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 343, 1949.
rat LD50 oral 4390mg/kg (4390mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

GASTROINTESTINAL: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.

Consensus Reports

Reported in EPA TSCA Inventory. Glycol ether compounds are on the Community Right-To-Know List.

Safety Profile

Hazard Codes :IrritantXi
Risk Statements: 10-37/38-41
R10:Flammable. 
R37/38:Irritating to respiratory system and skin. 
R41:Risk of serious damage to the eyes.
Safety Statements: 16-26-36
S16:Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
RIDADR: UN 1153 3/PG 2
WGK Germany: 2
RTECS :KI1225000
HazardClass: 3
PackingGroup: II
Moderately toxic by ingestion. Mildly toxic by inhalation. An experimental teratogen. Experimental reproductive effects. An eye irritant. An aprotic solvent. A very dangerous fire hazard when exposed to heat or flame; can react with oxidizing materials. To fight fire, use CO2, dry chemical.

Specification

 Ethylene glycol diethyl ether (CAS NO.629-14-1) can react with oxidizers. Ethylene glycol diethyl ether is incompatible with strong acids.It causes irritation of nose and throat. Contact with liquid irritates eyes but has little or no effect on skin. Ingestion causes irritation of mouth and stomach. Ethylene glycol diethyl ether (CAS NO.629-14-1) will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

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