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Basic information

  • Name:

  • 5,9:7,10a-Dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol,2-amino-1,4,4a,5,9,10-hexahydro-12-(hydroxymethyl)-,(4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-

  • Superlist Name:
  • Tetrodotoxin
  • CAS No.:

  • 4368-28-9

  • Formula:
  • C11H17 N3 O8
  • Synonyms:
  • 8a(1H)-Quinazolineorthoglycolicacid, octahydro-4,5,6,7,8-pentahydroxy-6-(hydroxymethyl)-2-imino-, cyclic8a,5:8a,7-ester (7CI); Tetrodotoxin (8CI); (-)-Tetrodotoxin;5,9:7,10a-Dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol,octahydro-12-(hydroxymethyl)-2-imino-, [4R-(4a,4aa,5a,7a,9a,10a,10ab,11S*,12S*)]-; Araregai toxin; BJT 1; Babyloniajaponica toxin 1; Maculotoxin; PFT-1 Toxin; Spheroidine; TTX; Tarichatoxin;Tetrodotoxine; [4R-(4a,4aa,5a,7a,9a,10a,10ab,11S*,12S*)]-Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol

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China (Mainland)(5)Japan(1)United Kingdom(1)United States(1)
Business Type:
Importer/Exporter(6)Lab/Research institutions(1)
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Chemistry

MF: C11H17N3O8
MW: 319.27
EINECS: 224-458-8
Product Categories: Living creature toxin;Sodium channel
Mol File: 4368-28-9.mol
storage temp：  2-8°C
solubility：  H2O: stable at pH 4-5 if stored frozensoluble
form：  powder
color：  white
Merck：  13,9318
Synonyms:FUGU POISON;TTX;TETRODOTOXIN;TETRODOTOXIN, FUGU SPECIES;OCTAHYDRO-12-(HYDROXYMETHYL)-2-IMINO-5,9:7,10A-DIMETHANO-10AH-[1,3]DIOXOCINO[6,5-D]PYRIMIDINE-4,7,10,11,12-PENTOL;10abeta,11s*,12s*))-10alph;12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10ah-(1,3)dioxocino(6,5-d)pyri;4aalpha,5alpha,7alpha,9alpha,10alpha,10abeta,11s*,12s*))-octahydro-(4r-(4alph
The structure of  FUGU POISON is: 

          

Toxicity Data With Reference

1.   

orl-mus LD50:435 µg/kg

   JJPAAZ    Japanese Journal of Pharmacology. 17 (1967),267.
2.   

ipr-mus LD50:8 µg/kg

   SCIEAS    Science. 144 (1964),1100.
3.   

scu-mus LD50:8 µg/kg

   CTOXAO    Clinical Toxicology. 4 (1971),331.
4.   

ivn-mus LD50:9 µg/kg

   JJPAAZ    Japanese Journal of Pharmacology. 17 (1967),267.

Consensus Reports

FUGU POISON(4368-28-9) is reported in EPA TSCA Inventory.

Safety Profile

Hazard Codes：  T+
Risk Statements：  26/27/28
Safety Statements：  22-36/37/39-45
RIDADR：  UN 3462 6.1/PG 1
WGK Germany：  3
RTECS：  IO1450000
F：  10-18
HazardClass：  6.1(a)
PackingGroup：  I
Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.

Specification

1、Fire Fighting Measures of  FUGU POISON(4368-28-9)
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.  Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. 
2、Handling and Storage of  FUGU POISON(4368-28-9)
Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. 
Storage: Store in a tightly closed container. Store in a dry area. Poison room locked/refrigerator. 

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