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Febuprol
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  • Name Febuprol
  • EINECS221-454-8
  • CAS No. 3102-00-9
  • Density1.034 g/cm3
  • PSA38.69000
  • LogP2.24300
  • SolubilityN/A
  • Melting Point25°C
  • FormulaC13H20 O3
  • Boiling Point346 °C at 760 mmHg
  • Molecular Weight224.3
  • Flash Point163.1 °C
  • Transport InformationN/A
  • AppearanceN/A
  • SafetyPoison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. Stimulates the production of bile by the liver. See also ETHERS. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Risk CodesN/A
  • Molecular Structure
    Molecular Structure of 3102-00-9 (Febuprol)
  • Hazard SymbolsN/A
  • SynonymsN/A
  • Article Data10

Febuprol Chemical Properties

Molecular Formula: C13H20O3
Molecular Weight: 224.30
EINECS: 221-454-8
Density: 1.034 g/cm3 
Flash Point: 163.1 °C 
Index of Refraction: 1.502
CAS Registry Number: 3102-00-9
Enthalpy of Vaporization: 62.28 kJ/mol 
Boiling Point: 346 °C at 760 mmHg 
Vapour Pressure: 2.25E-05 mmHg at 25°C 
IUPAC Name: 1-Butoxy-3-phenoxypropan-2-ol
Appearanceof 3-N-butoxy-1-phenoxy-2-propanol (CAS NO.3102-00-9): Colorless or slightly yellow transparent liquid
Solubility: Soluble in ether, methanol, anhydrous ethanol and acetone. almost insoluble in water.
Synonyms: (3-N-butoxy-2-hydroxypropyl)phenylether ; 1-Butoxy-3-phenoxy-2-propano ; 3-N-butoxy-1-phenoxy-2-propanol ; H-33 ; K-10033 ; 1-Butoxy-3-(phenoxy)propan-2-ol ; Febuprol
Following is the molecular structure of 3-N-butoxy-1-phenoxy-2-propanol (CAS NO.3102-00-9):

Febuprol Uses

 3-N-butoxy-1-phenoxy-2-propanol (CAS NO.3102-00-9) is a gallbladder drugs for the treatment of cholecystitis and cholelithiasis and postoperative hyperlipidemia, lipid dyspepsia, hepatitis embolism.

Febuprol Toxicity Data With Reference

1.    

orl-rat LD50:2370 mg/kg

     DRFUD4    Drugs of the Future. 3 (1978),191.
2.    

ipr-rat LD50:400 mg/kg

     DRFUD4    Drugs of the Future. 3 (1978),191.
3.    

orl-mus LD50:3050 mg/kg

     DRFUD4    Drugs of the Future. 3 (1978),191.
4.    

ipr-mus LD50:436 mg/kg

     DRFUD4    Drugs of the Future. 3 (1978),191.
5.    

orl-dog LD50:500 mg/kg

     DRFUD4    Drugs of the Future. 3 (1978),191.
6.    

ivn-dog LD50:150 mg/kg

     DRFUD4    Drugs of the Future. 3 (1978),191.

Febuprol Safety Profile

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. Stimulates the production of bile by the liver. When heated to decomposition it emits acrid smoke and irritating fumes.

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