Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Flugestone 17-acetate

Related Products

Hot Products

Basic Information Post buying leads Suppliers
Name

Flugestone 17-acetate

EINECS 219-776-9
CAS No. 2529-45-5 Density 1.244 g/cm3
PSA 80.67000 LogP 3.47210
Solubility N/A Melting Point 267.5ºC
Formula C23H31FO5 Boiling Point 526.653 °C at 760 mmHg
Molecular Weight 406.495 Flash Point 272.31 °C
Transport Information N/A Appearance COA
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 2529-45-5 (Flugestone 17-acetate) Hazard Symbols N/A
Synonyms

Pregn-4-ene-3,20-dione,9-fluoro-11b,17-dihydroxy-, 17-acetate(7CI,8CI);Progesterone, 9-fluoro-11b,17-dihydroxy-, 17-acetate (6CI);17a-Acetoxy-9a-fluoro-11b-hydroxy-pregn-4-ene-3,20-dione;17a-Acetoxy-9a-fluoro-11b-hydroxyprogesterone;9a-Fluoro-11b-hydroxy-17a-acetoxypregn-4-ene-3,20-dione;Chronogest;Cronolone;FGA;Flugestone acetate;Fluorogestone acetate;Flurogestone acetate;Gyncro-Mate;Synchronate;Syncro-MatePregn-4-ene-3,20-dione,17-(acetyloxy)-9-fluoro-11-hydroxy-, (11b)-;

 

Flugestone 17-acetate Synthetic route

337-03-1

9-fluoro-11β,17-dihydroxy-pregn-4-ene-3,20-dione

75-36-5

acetyl chloride

2529-45-5

fluorogestone acetate

Conditions
ConditionsYield
With triethylamine In chloroform at 10 - 65℃; Temperature;97.6%

C23H30O5

2529-45-5

fluorogestone acetate

Conditions
ConditionsYield
With hydrogen fluoride In N,N-dimethyl-formamide at -7 - -5℃; for 1h; Temperature;90%
24320-12-5, 94425-51-1

17-acetoxy-9,11β-epoxy-9β-pregn-4-ene-3,20-dione

2529-45-5

fluorogestone acetate

Conditions
ConditionsYield
With hydrogen fluoride
24320-15-8

17-acetoxy-9-bromo-11β-hydroxy-pregn-4-ene-3,20-dione

2529-45-5

fluorogestone acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium carbonate; water containing tetrahydrofuran
2: HF
View Scheme
34184-82-2

pregna-4,9(11)-diene-3,20-dione-17-hydroxy-21-methyl

2529-45-5

fluorogestone acetate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: toluene-4-sulfonic acid / 1.25 h / 40 - 50 °C / Inert atmosphere
2: perchloric acid; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione / acetone; water / 2.17 h / 0 - 60 °C / Inert atmosphere
3: potassium carbonate / acetone; water / 5.5 h / 0 - 3 °C / Inert atmosphere
4: hydrogen fluoride / N,N-dimethyl-formamide / 1 h / -7 - -5 °C
View Scheme
5106-48-9

17-acetoxy-pregna-4,9(11)-diene-3,20-dione

2529-45-5

fluorogestone acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: perchloric acid; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione / acetone; water / 2.17 h / 0 - 60 °C / Inert atmosphere
2: potassium carbonate / acetone; water / 5.5 h / 0 - 3 °C / Inert atmosphere
3: hydrogen fluoride / N,N-dimethyl-formamide / 1 h / -7 - -5 °C
View Scheme
127-31-1

Fludrocortisone

2529-45-5

fluorogestone acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: triethylamine; p-toluenesulfonyl chloride / dichloromethane; toluene / 40 - 45 °C
2: sodium iodide; sodium dithionite / ethanol; water / 80 - 85 °C
3: triethylamine / chloroform / 10 - 65 °C
View Scheme
2529-45-5

fluorogestone acetate

377-26-4

17-acetoxy-9-fluoro-pregn-4-ene-3,11,20-trione

Conditions
ConditionsYield
With pyridine; chromium(VI) oxide

Flugestone 17-acetate Chemical Properties


IUPAC Name: [(8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-fluoro-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate
Molecular Weight: 406.487643 [g/mol]
Molecular Formula: C23H31FO5
XLogP3: 2.3
H-Bond Donor: 1
H-Bond Acceptor: 6 
EINECS: 219-776-9 
Index of Refraction: 1.548
Molar Refractivity: 103.767 cm3
Molar Volume: 326.69 cm3 
Surface Tension: 47.655 dyne/cm
Density: 1.244 g/cm3
Flash Point: 272.31 °C
Enthalpy of Vaporization: 92.16 kJ/mol
Boiling Point: 526.653 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25 °C
Melting Point: 267.5 °C
Classification Code of Flugestone 17-acetate (CAS NO.2529-45-5): Progestin; Reproductive Effect

Flugestone 17-acetate Specification

  Flugestone 17-acetate (CAS NO.2529-45-5), its Synonyms are 9-Fluoro-11beta,17-dihydroxypregn-4-ene-3,20-dione 17-acetate ; 9alpha-Fluoro-11-hydroxy,17alpha-acetoxy progesterone ; Cronolone ; FGA ; Fluorogesterone acetate ; Fluorogestone acetate ; Flurogestone acetate ; Gyncro-mate ; Synchro-mate ; Pregn-4-ene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-, (11beta)- ; Pregn-4-ene-3,20-dione, 9-fluoro-11-beta,17-dihydroxy-, 17-acetate .

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 2529-45-5