- Fluoxetine
- Fluoxetine hydrochloride
- Fluoxetine hydrochloride
- 54-91-11-Propanone,1,1'-(1,4-piperazinediyl)bis[3-bromo-
- 54914-8-51,2-Bis(m-tolyloxy)ethane
- 54914-85-1Benzene,1,1'-[1,2-ethanediylbis(oxy)]bis[3-methyl-
- 54916-27-7Ethanone,1-[4-(4-bromophenoxy)phenyl]-
- 54916-28-8Ethanone,1-[4-(4-methoxyphenoxy)phenyl]-
- 54916-66-43-Pyridinecarboxylicacid, 5-bromo-2-methoxy-
- 549-18-8Amitriptyline hydrochloride
- 54920-82-01,3-Naphthyridine-2 (1H)-one
- 54920-83-11,7-Naphthyridine,2-bromo-
- 54923-31-82(1H)-Pyridinone,5-bromo-6-methyl-
Hot Products
- 97540-22-2Ademetionine disulfate tosylate
- 98-29-34-tert-Butylcatechol
- 108-83-84-Heptanone,2,6-dimethyl-
- 50-84-02,4-Dichlorobenzoic acid
- 53179-13-8Pirfenidone
- 87616-84-0L-Lysinamide,L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-
- 55406-53-6Carbamic acid,N-butyl-, 3-iodo-2-propyn-1-yl ester
- 70415-50-86-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic acid methyl ester 1,1-dioxide
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Fluoxetine |
EINECS | 611-209-7 |
| CAS No. | 54910-89-3 | Density | 1.159 g/cm3 |
| PSA | 21.26000 | LogP | 4.82590 |
| Solubility | Insoluble in water | Melting Point |
158oC |
| Formula | C17H18F3NO | Boiling Point | 395.1 °C at 760 mmHg |
| Molecular Weight | 309.331 | Flash Point | 192.8 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | R34; R36/37; R36/37/38 | |
| Molecular Structure |
|
Hazard Symbols |
 C, Xi
|
| Synonyms |
Fluoxetine (TN);Fluoxetine (USAN);(+/-)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine];Prozac;dl-3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine;Pulvules;Fluval;3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine;Benzenepropanamine, N-methyl-gamma-[4-(trifluoromethyl)phenoxy]-, (+/-)-; |
Article Data | 65 |
Fluoxetine Chemical Properties
Molecular Structure of Fluoxetine (CAS NO.491878-06-9):
IUPAC Name: N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
Empirical Formula: C17H18F3NO
Molecular Weight: 309.33
H bond acceptors: 2
H bond donors: 1
Freely Rotating Bonds: 6
Polar Surface Area: 12.47Å2
Index of Refraction: 1.51
Molar Refractivity of Fluoxetine (CAS NO.491878-06-9): 79.89 cm3
Molar Volume: 266.7 cm3
Surface Tension: 32.9 dyne/cm
Density: 1.159 g/cm3
Flash Point: 192.8 °C
Enthalpy of Vaporization: 64.52 kJ/mol
Boiling Point: 395.1 °C at 760 mmHg
Vapour Pressure: 1.88E-06 mmHg at 25°C
pKa/pKb: 3.95 (pKb)
Partition Coefficient: 3.749
Solubility in water: Insoluble
InChI
InChI=1/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3
Smiles
c1([C@@H](Oc2ccc(C(F)(F)F)cc2)CCNC)ccccc1
Classification Code of Fluoxetine (CAS NO.491878-06-9): Antidepressant; Antidepressive Agents; Antidepressive agents, second-generation; Central Nervous System Agents; Drug / Therapeutic Agent; Human Data; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Psychotropic Drugs; Reproductive Effect; Serotonin Agents; Serotonin uptake inhibitors
Fluoxetine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| man | TDLo | oral | 17mg/kg (17mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | American Journal of Emergency Medicine. Vol. 16, Pg. 328, 1998. |
| man | TDLo | oral | 17mg/kg (17mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | American Journal of Emergency Medicine. Vol. 16, Pg. 328, 1998. |
| mouse | LD50 | intraperitoneal | 87500ug/kg (87.5mg/kg) | Drugs of the Future. Vol. 15, Pg. 1178, 1990. | |
| mouse | LD50 | oral | 464mg/kg (464mg/kg) | Drugs of the Future. Vol. 15, Pg. 1178, 1990. | |
| rat | LD50 | intraperitoneal | 121mg/kg (121mg/kg) | Drugs of the Future. Vol. 15, Pg. 1178, 1990. | |
| rat | LD50 | oral | 825mg/kg (825mg/kg) | Drugs of the Future. Vol. 15, Pg. 1178, 1990. | |
| women | TDLo | oral | 2mg/kg/5D-I (2mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Archives of Internal Medicine. Vol. 156, Pg. 681, 1996. |
| women | TDLo | oral | 16800ug/kg/6W (16.8mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ANTIPSYCHOTIC | Archives of Internal Medicine. Vol. 156, Pg. 681, 1996. |
| women | TDLo | oral | 60mg/kg/21W-I (60mg/kg) | American Journal of Psychiatry. Vol. 153, Pg. 134, 1996. | |
| women | TDLo | oral | 72mg/kg/26W-I (72mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Clinical Pyschopharmacology. Vol. 10, Pg. 343, 1990. |
Fluoxetine Specification
Fluoxetine , with CAS number of 491878-06-9, can be called (+) or (-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine ; (+) or (-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine ; (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine ; (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine ; Benzenepropamine, N-methyl-gamma-(4-(trifluoromethyl)phenoxy)-, (+-)- .
What can I do for you?
Get Best Price
