Basic Information | Post buying leads | Suppliers |
Name |
Fluoxymesterone |
EINECS | 200-961-8 |
CAS No. | 76-43-7 | Density | 1.22 g/cm3 |
PSA | 57.53000 | LogP | 3.33220 |
Solubility | water: ≤0.5 mg/mL | Melting Point |
240 °C |
Formula | C20H29FO3 | Boiling Point | 474.2 °C at 760 mmHg |
Molecular Weight | 336.447 | Flash Point | 240.6 °C |
Transport Information | N/A | Appearance | white to light yellow crystal powder |
Safety | 22-36-24/25 | Risk Codes | 63 |
Molecular Structure | Hazard Symbols | Xn | |
Synonyms |
9-Fluoro-11b,17b-dihydroxy-17-methylandrost-4-en-3-one;9a-Fluoro-11b,17b-dihydroxy-17a-methylandrost-4-ene-3-one;9a-Fluoro-11b-hydroxy-17a-methyltestosterone;Androfluorone;Androsterolo;Fluotestin;Flusteron;Flutestos;Halotestin;NSC 10704;NSC-12165;Neo-Ormonal;Ora Testryl;Oralsterone;Oratestin;Testoral;U 6040;Ultandren;Ultandrene;Androst-4-en-3-one,9-fluoro-11b,17b-dihydroxy-17-methyl- (6CI,8CI);17a-Methyl-9a-fluoro-11b-hydroxytestosterone; |
The IUPAC name of Androfluorene is (8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one. With the CAS registry number 76-43-7, it is also named as Fluoxymesterone. The classification codes are Anabolic Agents; Androgen; Drug / Therapeutic Agent; Hormones, Hormone Substitutes, and Hormone Antagonists; Human Data; Mutation data; Reproductive Effect. Additionally, Androfluorene is white to light yellow crystal powder which is toxic and flammable. It will produce toxic nitrogen oxide fumes when buring. So the storage environment should be ventilate, low-temperature and dry. Furthermore, this chemical is used in biochemistry research.
The other characteristics of this product can be summarized as: (1)ACD/LogP: 2.17; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.17; (4)ACD/LogD (pH 7.4): 2.17; (5)ACD/BCF (pH 5.5): 26.12; (6)ACD/BCF (pH 7.4): 26.12; (7)ACD/KOC (pH 5.5): 359.62; (8)ACD/KOC (pH 7.4): 359.62; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.562; (13)Molar Refractivity: 89.43 cm3; (14)Molar Volume: 275.7 cm3; (15)Polarizability: 35.45×10-24 cm3; (16)Surface Tension: 47.6 dyne/cm; (17)Enthalpy of Vaporization: 85.02 kJ/mol; (18)Vapour Pressure: 5.5E-11 mmHg at 25°C; (19)Tautomer Count: 5; (20)Exact Mass: 336.210073; (21)MonoIsotopic Mass: 336.210073; (22)Topological Polar Surface Area: 57.5; (23)Heavy Atom Count: 24; (24)Complexity: 630.
When you are using this chemical, please be cautious about it as the following:
Avoid breathing dust, vapor, mist, or gas, avoid contact with skin and eyes and avoid ingestion and inhalation. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
People can use the following data to convert to the molecule structure.
1. SMILES:O=C4\C=C3/[C@]([C@@]2(F)[C@@H](O)C[C@]1([C@@H](CC[C@@]1(O)C)[C@@H]2CC3)C)(C)CC4
2. InChI:InChI=1/C20H29FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h10,14-16,23-24H,4-9,11H2,1-3H3/t14-,15-,16-,17-,18-,19-,20-/m0/s1
The following are the toxicity data which has been tested.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
human | TDLo | oral | 400ug/kg (0.4mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Cancer Vol. 41, Pg. 758, 1978. |
mouse | LD50 | intraperitoneal | 2350mg/kg (2350mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 623, 1977. |