Journal of Medicinal Chemistry p. 11383 - 11398 (2019)
Update date:2022-08-15
Topics:
Pettinger, Jonathan
Carter, Michael
Jones, Keith
Cheeseman, Matthew D.
The covalent inhibition mechanism of action, which overcomes competition with high-affinity, high-abundance substrates of challenging protein targets, can deliver effective chemical probes and drugs. The success of this strategy has centered on exposed cy
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