Organic Letters
Letter
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excellent yields. Of particular importance is the fact that this
reagent system was suitable for the synthesis of dipeptides from
sterically hindered amino acids. The reactions proceeded
without racemization, and 1a could be regenerated conven-
iently, making this method an attractive alternative to
traditional methods for peptide coupling.
ASSOCIATED CONTENT
* Supporting Information
■
S
The Supporting Information is available free of charge on the
Experimental details, characterization data for new
compounds, 1H, 13C, and 19F NMR spectra, and
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AUTHOR INFORMATION
Corresponding Author
■
Notes
The authors declare no competing financial interest.
ACKNOWLEDGMENTS
■
This work was financially supported by The National Natural
Science Foundation of China (21172110, 21472094, and
21421062).
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