Journal of Medicinal Chemistry p. 2810 - 2816 (1993)
Update date:2022-08-02
Topics: Synthesis Derivatives Naphthalene Structure-activity relationships Antimycotic Allylamine Terbinafine
Nussbaumer, Peter
Dorfstaetter, Gerhard
Leitner, Ingrid
Mraz, Karin
Vypel, Hermann
Stuetz, Anton
Derivatives of the allylamine antimycotic terbinafine (1) with varied substitution at the naphthalene ring system have been prepared, and their antifungal activity has been evaluated.In general, the potency is strongly dependent on the bulkiness of the su
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