Bioorganic and Medicinal Chemistry Letters p. 2284 - 2288 (2016)
Update date:2022-08-05
Topics:
Wu, Xiaoai
Fang, Zhen
Yang, Bo
Zhong, Lei
Yang, Qiuyuan
Zhang, Chunhui
Huang, Shenzhen
Xiang, Rong
Suzuki, Takayoshi
Li, Lin-Li
Yang, Sheng-Yong
Herein we report the discovery of a series of new KDM5A inhibitors. A three-dimensional (3D) structure model of KDM5A jumonji domain was firstly established based on homology modeling. Molecular docking-based virtual screening was then performed against c
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