Journal of Agricultural and Food Chemistry p. 828 - 833 (1994)
Update date:2022-08-02
Topics:
Lauren, Denis R.
Smith, Wendy A.
Wilkins, Alistair L.
4,15-Diacetylnivalenol (DANIV) was produced in liquid culture and purified by fractionation over silica followed by preparative liquid chromatography.Hydrolysis gave nivalenol (NIV), a trichothecene mycotoxin found as a common contaminant in grain grown in the North Island of New Zealand.Reaction of NIV with succinic anhydride in the presence of n-butylboronic acid and (dimethylamino)pyridine produced a mixture of three mono- and two dihemisuccinates.These were separated by semipreparative HPLC.The major product was 3-hemisuccinyl-NIV (3-HS-NIV).Other products were 4-HS-NIV, 15-HS-NIV, 3,4-diHS-NIV, and 3,15-diHS-NIV. 3-HS-NIV was also produced by enzymatic hydrolysis of 3-HS-DANIV.
View MoreContact:+86-21-61318535
Address:Building 29,No.2139 Xizha Road, Fengxian District, Shanghai
Chengdu D-Innovation Pharmaceutical Co., Ltd
Contact:86-28-85105536
Address:1001, B6, No.88 Keyuan South Road, Chengdu Hi-Tech Zone
Airsea(Taizhou) Pharmaceutical Limited
Contact:+86-576-88057622
Address:Dubei, Duqiao, Linhai, Taizhou, Zhejiang, China Zip: 317016
Contact:+86-571-86025531 / 86024803
Address:1218-24 Guangyin Mansion,42 Fengqi East Road
Quzhou Ruiyuan chemical Co., Ltd
Contact:+86-570-3039321/3039361/3039308
Address:18# Huayang Road,Quzhou High-tech Industrial Park, Zhejiang China.
Doi:10.1016/S0040-4020(01)81544-1
(1993)Doi:10.1002/ardp.19943270310
(1994)Doi:10.1021/ol403741m
(2014)Doi:10.1248/cpb.41.1933
(1993)Doi:10.1016/S0040-4039(00)61395-3
(1993)Doi:10.1002/recl.19931121005
(1993)