Bioorganic and Medicinal Chemistry Letters p. 1015 - 1020 (1996)
Update date:2022-08-04
Topics:
Armour
Chung
Congreve
Evans
Guntrip
Hubbard
Kay
Middlemiss
Mordaunt
Pegg
Vinader
Ward
Watson
The medicinal chemistry strategy which led to the identification of GR205171, an orally active non-peptide neurokinin-1 receptor antagonist that is the most potent broad-spectrum antiemetic agent reported to date.
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