Nucleosides, nucleotides and nucleic acids p. 348 - 360 (2015)
Update date:2022-08-05
Topics:
Gibbons, Garrett S.
Showalter, Hollis D.
Nikolovska-Coleska, Zaneta
Modifications of the 5′-position of adenosine have been prepared via a novel 5′-carboxaldehyde synthon. The described methodology should prove useful for making related compounds in which amine-derived moieties off the 5′-position of adenosine (or related nucleoside congeners) can be easily incorporated via reductive amination, especially for the incorporation of aromatic amines.
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