Tetrahedron p. 13315 - 13322 (1997)
Update date:2022-07-29
Topics:
Kitano, Kenji
Miura, Shinji
Ohrui, Hiroshi
Meguro, Hiroshi
2-Deoxy-D-erythro-, ribo-, and arabino-pentofuranosylcytosines, which have a fluoromethyl group at the 4'-position, were synthesized. Introduction of fluorine was achieved by DAST treatment of 4-C-hydoxymethy]-D-ribofuranose, the key intermediate of 4'-C-methylnucleosides. Among these nucleosides, the 2'-deoxy derivative exhibited potent antineoplastic activity in vitro.
View MoreSHANDONG CREDAGRI CHEMICAL CO., LTD.
Contact:+86-531-88872050
Address:ROOM 601A, BUILDING 2, SHUNTAI SQUARE, NO. 2000 SHUNHUA ROAD, HI-TECH DEVELOPMENT ZONE, JINAN, CHINA.
Contact:+86 0310 3166373
Address:shanghai
Chengdu King-tiger Pharm-chem. Tech. Co., Ltd
Contact:028-85317716
Address:Tianfu Life Science Park, No. 88 South Keyuan Road, Gaoxin District, Chengdu City, Sichuan Province, PRC.
Zhejiang Haizhou Pharmaceutical Co., Ltd.
website:https://www.haizhoupharma.com/
Contact:+86 576 88221016
Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Contact:0572-2722882
Address:1201,F3,xinghuibandao,
Doi:10.1021/op900296p
(2010)Doi:10.1016/S0040-4039(00)76742-6
(1994)Doi:10.1016/S0960-894X(97)00432-0
(1997)Doi:10.1021/jo970947s
(1997)Doi:10.3797/scipharm.aut-00-09
(2000)Doi:10.1016/S0040-4020(98)00057-X
(1998)