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Conclusions
The iron-catalysed allylation of alkyl and aryl Grignard reagents
with allyl acetate derivatives operates under very mild condi-
tions with a commercial catalyst. Kinetic experiments suggest
a highly active homotopic catalyst. Slow Grignard addition
protocols or the presence of electrophilic additives (e.g. chlo-
roform) enhanced catalyst activity and lifetime. The sequential
combination of the iron-catalysed allylation of alkyl-magnesium
halides with an iron-catalysed hydrogenation of the resultant
alkenes results in a formal sp3–sp3-cross-coupling that proved
otherwise challenging. The presence of high bromide concen-
trations inhibited the hydrogenation step.
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Conflicts of interest
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There are no conicts to declare.
Acknowledgements
This work was generously supported by the European Research
Council (CoG 683150) and the University of Hamburg.
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31222 | RSC Adv., 2019, 9, 31217–31223
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