Site-Directed Affinity Reagent for Cross-Linking Human Hb
Journal of Medicinal Chemistry, 2004, Vol. 47, No. 24 5859
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grateful to Dr. Susanne Hoffmann-Benning of the
Michigan State University Mass Spectrometry Facility,
East Lansing, MI, for the reported MALDI mass specral
data. We are also thankful to Colonel John Hess of the
Department of Blood Research, Walter Reed Army
Institute of Research for the generous gift of stroma-
free hemoglobin employed in our studies and to Mrs.
Charlotte Gomez of that department for her help in
generating the hemoglobin oxygen binding data.
Supporting Information Available: Elemental micro-
analytical data for compounds 1, 3, 4, 5, 7, and 8. This mate-
rial is available free of charge via the Internet at http://
pubs.acs.org.
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