Synthetic Communications p. 2809 - 2814 (2018)
Update date:2022-08-17
Topics:
Kristianslund, Renate
Vik, Anders
Hansen, Trond V.
Anilines are rapidly, often within 60 minutes, converted into the corresponding phenols in up to 87% isolated yield. The presented experimentally simple protocol display broad compatibility with a variety of functional groups, and in particular, well suited for the preparation of methyl-substituted phenols. Such phenols are not easily available by other synthetic approaches. The formation of phenolic radical coupling products was not observed even for activated anilines using this open flask method.
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