Supramolecular Helical Architectures
FULL PAPER
and the hydroxy hydrogen atom of 1b. These double inter-
actions resulted in the stable inclusion of molecules of 3 in
the cavities. The present results indicate that various host
systems with supramolecular architectures can be construct-
ed from combinations of enantiopure/achiral primary
amines and achiral/enantiopure carboxylic acids and that
such multicomponent host systems could be applied to mo-
lecular recognition, asymmetric reactions, and so on.
Acknowledgements
We are grateful to Prof. Takuzo Aida, ERATO Nanospace Project, JST,
for permission to use the single-crystal X-ray diffractometer. We thank
Dr. Kenji Yoza, Bruker-AXS K.K., for a crystallographic analysis.
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Experimental Section
[
General methods: All of the alcohols except for 3a, 3p, and 3q were syn-
thesized by reduction of the corresponding carbonyl compounds and
1
were identified by H NMR spectroscopy. The alcohol 3p was prepared
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1
purification. H NMR spectra of the inclusion crystals in CDCl
3
/CD
3
OD
were measured with a 300 MHz NMR instrument. IR spectra were mea-
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À1
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2
)The suspension method: The salt was added to a hexane solution of a
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[
The inclusion ratios of the alcohols in the three-component crystals were
1
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(
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2
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2
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2151