Potassium hydroxide-promoted transition-metal-free synthesis
2
-(3-Methylphenyl)benzofuro[3,2-d]pyrimidin-4(3H)-one
20. Wang G-W, Miao C-B, Kang H (2006) Bull Chem Soc Japan
9:1426
7
(
3u, C H N O )
1
7 12 2 2
2
1. Wang X-S, Yang K, Zhang M-M, Yao C-S (2010) Synth Com-
mun 40:2633
1
Yield: 48 %; white solid; m.p.: 291–293 °C; H NMR
300 MHz, DMSO-d ): d = 13.06 (s, 1H), 8.13 (d,
J = 7.7 Hz, 1H), 8.06–7.91 (m, 2H), 7.86 (d,
(
22. Zhan D, Li T, Zhang X, Dai C, Wei H, Zhang Y, Zeng Q (2013)
Synth Commun 43:2493
6
2
3. Zhan D, Li T, Wei H, Weng W, Ghandi K, Zeng Q (2013) RSC
Adv 3:9325
4. Kim NY, Cheon C-H (2014) Tetrahedron Lett 55:2340
J = 8.3 Hz, 1H), 7.70 (t, J = 7.6 Hz, 1H), 7.63–7.34 (m,
1
H), 7.17–6.93 (m, 1H), 2.42 (s, 3H) ppm; C NMR
3
3
2
(
101 MHz, DMSO-d ): d = 156.3, 154.5, 153.4, 138.1,
37.9, 131.9, 129.9, 129.1, 128.6, 128.5, 128.1, 127.7,
25.4, 125.1, 124.4, 122.4, 121.4, 113.0, 20.9 ppm; IR
25. Takeuchi H, Haguvara S, Eguchi S (1989) Tetrahedron 45:6375
26. Connolly DJ, Guiry PJ (2001) Synlett 11:1707
6
1
1
2
2
2
7. Xu W, Jin Y, Liu H, Jiang Y, Fu H (2011) Org Lett 13:1274
8. Wei H, Li T, Zhou Y, Zhou L, Zeng Q (2013) Synthesis 45:3349
9. Chen J, Wu D, He F, Liu M, Wu H, Ding J, Su W (2008) Te-
trahedron Lett 49:3814
(
KBr): mꢀ = 3,560, 2,076, 1,637, 1,391, 1,085, 991,
-
46 cm .
1
5
3
0. Mohammadi AA, SadatHossini SS (2011) Chin J Chem 29:1982
Acknowledgments We appreciate Allan Kipruto Chelashaws& help.
We thank the National Natural Science Foundation of China (No.
21372034) and the cultivating program for excellent innovation team
of Chengdu University of Technology for financial support.
31. Zhou J, Fang J (2011) J Org Chem 76:7730
32. Watson AJA, Maxwell AC, Williams JM (2012) J Org Biomol
Chem 10:240
33. Hikawa H, Ino Y, Suzuki H, Yokoyama Y (2012) J Org Chem
7
7:7046
4. Sharif M, Opalach J, Langer P, Beller M, Wu MF (2014) RSC
Adv 4:8
3
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