ARTICLE
applied to specific rotation measurement while the chiral
nanoparticles were washed with ethanol three times before
dried for the next use. Each time after separation, we
deducted the lost nanoparticles out then suspended the
remaining in a corresponding amount of ethanol dissolved
D,L-tartaric acid. In this way four separation–abstersion
cycles were performed. As shown in Figure 6, the nanopar-
ticles can be reused well; however, the separation ability has
somewhat loss after each cycle. This is attributable to the
fact that the crosslinked nanoparticles could not disperse
well in ethanol solution when dried and reused to next cycle,
due to some of the agglomerations or collapsed nanopar-
ticles was occurred while most of the nanoparticles still kept
the same morphology after four times of chiral separation,
which resulted in some loss of the specific area.
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A novel way for the synthesis of well-defined chiral poly-
(
VBPG) homopolymers and corresponding crosslinked nano-
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mulsion polymerization using linear poly(VBPG) as the
macro-RAFT agent, was demonstrated. The kinetics of RAFT
miniemulsion polymerization of VBPG suggested that the
polymerization proceeded in a living fashion. The amount of
crosslinker had a significant effect on the size and chiral sep-
aration ability of the obtained crosslinked nanoparticles. It
was found that the efficiency of chiral separation was greatly
improved after transferring the crosslinked structure into
the nanoparticles when compared with the chiral linear
chains and that 3–6 wt % of DVB relative to the chiral
monomer VBPG could give the crosslinked chiral nanopar-
ticles better chiral separation ability for the different kinds
of racemates such as D,L-arabinose and (6)-3-amino-1,2-pro-
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up to 9 wt %, the ability decreased rapidly.
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