Synthetic Communications p. 3344 - 3360 (2012)
Update date:2022-08-28
Topics:
Gangula, Srinivas
Kolla, Naveen Kumar
Elati, Chandrasekar
Dongamanti, Ashok
Bandichhor, Rakeshwar
An efficient process for production of paroxetine hydrochloride hemihydrate 1, a selective 5-hydroxytryptamine (serotonin) reuptake inhibitor, is described. Identification and control of potential impurities and establishment of efficient downstream workup procedures enabled us to produce paroxetine hydrochloride hemihydrate 1 efficiently.
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Doi:10.1016/S0022-328X(00)80193-X
(1965)Doi:10.1002/cctc.201300529
(2013)Doi:10.1002/cssc.201903545
(2020)Doi:10.1007/BF01512030
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(2020)Doi:10.1039/P29930002209
(1993)