Tetrahedron Letters p. 5581 - 5582 (1999)
Update date:2022-08-11
Topics:
Jo, Eunyoung
Na, Youngim
Chang, Sukbok
Optically active (S)-(+)-coniine as an N-Boc protected form was concisely prepared starting from an amino acid, L-norvaline. The key step involved a ring-closing olefin metathesis (RCM) of the dialkenyl compound 6 to give the corresponding cyclic olefin 8 in an essentially quantitative yield.
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