Antiviral activity of 2,3′-anhydro and related pyrimidine nucleosides against hepatitis B virus

DOI: 10.1016/j.bmcl.2010.08.120

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 6790 - 6793 (2010)

Update date:2022-08-28

Topics:

Authors:

Srivastav, Naveen C.

Mak, Michelle

Agrawal, Babita

Tyrrell, D. Lorne J.

Kumar, Rakesh

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Article abstract of DOI:10.1016/j.bmcl.2010.08.120

Various 2,3′-anhydro analogs of 5-substituted 1-(2-deoxy-β-d- lyxofuranosyl)uracils (10-15) and a related 1-(3-O-mesyl-2-deoxy-β-d- lyxofuranosyl) pyrimidine nucleoside analog (18) have been synthesized for evaluation as a new class of potential anti-HBV

Full text of DOI:10.1016/j.bmcl.2010.08.120

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