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Table 3
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In conclusion, we have described a simple, convenient and effi-
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aryl-4,5-diphenyl-1H-imidazoles in water. The simplicity, effi-
ciency, mild reaction condition, high yields of products, easy
work-up procedure, and using very small amounts of [Hmim]TFA
make it one of the preferred procedures for the preparation of dif-
ferentially substituted imidazoles. Another important feature of
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3
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2. Typical procedure for the preparation of imidazole derivatives: A mixture of
benzil or benzoin (1 mmol), aldehyde (1 mmol), ammonium acetate (2 mmol),
and [Hmim]TFA (10 mmol %) was heated in water (10 mL) at 80 °C with
vigorous stirring until TLC showed completion of the reaction (approximates
Acknowledgments
6
We gratefully acknowledge financial support from the Research
Council of Shahid Beheshti University. We also acknowledge sup-
port from the University of New Brunswick.