Tetrahedron Letters p. 5501 - 5504 (1998)
Update date:2022-08-17
Topics:
Wang, Zhe
La, Brittany
Fortunak, Joseph M.
Meng, Xian-Jun
Kabalka, George W.
α-Oxocarboxylic acids can be reduced to the corresponding α-hydroxy carboxylic acids employing DIP-CI(TM) as a reducing agent. The α-carboxylic substituent exerts a remarkable neighboring group effect on the reduction. The reaction presumably proceeds in an intramolecular fashion through a 'rigid' bicyclic transition state assembly, which produces enantioselectivities approaching 99%.
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Doi:10.1016/j.tetlet.2017.02.079
(2017)Doi:10.1080/10426500008042105
(2000)Doi:10.1021/jo00337a029
(1981)Doi:10.1016/S0957-4166(00)86050-4
(1992)Doi:10.1016/S0040-4039(98)01346-X
(1998)Doi:10.1016/j.tetlet.2004.01.129
(2004)