Journal of Heterocyclic Chemistry p. 1211 - 1215 (1996)
Update date:2022-08-11
Topics:
Levacher, Vincent
Valque, Claude
Coupa, Sophie
Dupas, Georges
Queguiner, Guy
Bourguignon, Jean
Reduction of 2,2-diphenyl-1-nitroethylene (1) and 2-(2-pyridyl)-2-phenyl-1-nitroethylene (5) is achieved by using the NADH model in the pyrrolopyridine series 2a to give 2,2-diphenyl-1-nitroethane (3) and 2-(2-pyridyl)-2-phenyl-1-nitroethane (7) respectively in 40% yield. The asymmetric reduction of 2-(2-pyridyl)-2-phenyl-1-nitroethylene by the chiral NADH model 2b is studied. Thus, 2-(2-pyridyl)-2-phenyl-1-nitroethane (7) is obtained in 15 to 32% yield. The stereocontrol of the reduction proved to be dependent on the amount of magnesium ions.
View MoreContact:0086-357-6662688
Address:Zhaocheng town, Hongtong County, Linfen City, Shanxi Province
Contact:86-310-8067016
Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Dalian Synco Chemical Co., Ltd.
Contact:+86-411-83635150
Address:Rm 1004, 24, Tangshan Street, Dalian
Contact:+1-416-493-6870
Address:Toronto, Canada
shijiazhuang baisheng chem co.; ltd
Contact:86-0311-80790826
Address:shijiazhuang hebei
Doi:10.1055/s-0039-1690204
(2019)Doi:10.1002/zaac.19332140108
(1933)Doi:10.1002/aoc.4188
(2018)Doi:10.1021/jo00127a029
(1995)Doi:10.1016/j.bmc.2003.12.012
(2004)Doi:10.1016/j.tet.2007.10.065
(2008)