1914
Yang, Liang:
167.0, 154.2, 136.5, 130.4, 129.9, 129.4, 128.8, 128.1, 126.5, 126.2, 125.6, 123.1, 122.0. For
13H8ClNS (245.0) calculated: 63.54% C, 3.28% H, 5.70% N, 13.05% S; found: 63.58% C,
C
3.23% H, 5.60% N, 13.10% S.
2-(2-Chlorophenyl)-1,3-benzothiazole (3i). Yield 83%, yellow soild, m.p. 85–86 (81–83)17
.
1H NMR (CDCl3): 8.26–8.19 m, 1 H (Ar-H); 8.15 d, 1 H, J = 8.0 (Ar-H); 7.98 d, 1 H, J = 7.6
(Ar-H); 7.56–7.51 m, 2 H (Ar-H); 7.46–7.35 m, 3 H (Ar-H). 13C NMR (CDCl3): 166.4, 154.2,
137.1, 133.4, 132.6, 132.0, 131.5, 130.3, 127.0, 126.6, 125.8, 122.9, 121.8. For C13H8ClNS
(245.0) calculated: 63.54% C, 3.28% H, 5.70% N, 13.05% S; found: 63.63% C, 3.20% H,
5.74% N, 13.12% S.
2-(2-Methoxyphenyl)-1,3-benzothiazole (3j). Yield 89%, white soild, m.p. 105–106 °C
(106–108 °C)22 1H NMR (CDCl3): 8.60–7.10 m, 8 H (Ar-H); 3.98 s, 3 H (OMe). 13C NMR
.
(CDCl3): 164.2, 158.0, 153.4, 138.5, 132.2, 130.1, 126.2, 124.9, 122.6, 122.5, 121.1, 120.9,
112.4, 56.2. For C14H11NOS (241.3) calculated: 69.68% C, 4.59% H, 5.80% N, 13.29% S;
found: 69.75% C, 4.51% H, 5.72% N, 13.40% S.
2-(Benzo[1,3] dioxol-5-yl)-1,3-benzothiazole (3k). Yield 90%, white soild, m.p. 122–123 °C
(124–126 °C)22 1H NMR (CDCl3): 8.09 d, 1 H, J = 8.0 (Ar-H); 7.95 d, 1 H, J = 8.0 (Ar-H);
.
7.66–7.35 m, 4 H (Ar-H); 7.03 d, 1 H, J = 8.0 (Ar-H); 6.12 s, 2 H (OCH2O). 13C NMR (CDCl3):
167.2, 155.2, 149.9, 147.9, 135.4, 128.8, 126.8, 125.2, 123.0, 122.6, 122.0, 108.7, 108.0,
102.1. For C14H9NO2S (255.0) calculated: 65.87% C, 3.55% H, 5.49% N, 12.56% S; found:
65.91% C, 3.50% H, 5.61% N, 12.70% S.
2-(Pyridin-2-yl)-1,3-benzothiazole (3l). Yield 90%, white soild, m.p. 131–132 °C (131–133 °C)22
.
1H NMR (CDCl3): 8.66–8.02 m, 3 H (Ar-H); 7.92–7.77 m, 2 H (Ar-H); 7.51–7.35 m, 2 H
(Ar-H). 13C NMR (CDCl3): 168.9, 155.6, 151.3, 150.0, 138.4, 136,5, 126.6, 126.0, 125.5,
124.1, 123.0, 121.1. For C12H8N2S (212.0) calculated: 67.90% C, 3.80% H, 13.20% N,
15.11% S; found: 68.00% C, 3.65% H, 13.16% N, 15.06% S.
2-(Furan-2-yl)benzo[d]thiazole (3m). Yield 89%, yellow soild, m.p. 103–105 °C (103–104 °C)21
.
1H NMR (CDCl3): 8.10–6.63 m, 7 H (Ar-H). 13C NMR (CDCl3,): 158.0, 151.2, 148.7, 142.8,
132.9, 126.0, 125.7, 124.1, 120.8, 112.9, 112.1. For C11H7NOS (201.0) calculated: 65.65% C,
3.51% H, 6.96% N, 15.93% S; found: 65.80% C, 3.27% H, 7.05% N, 15.99% S.
We are pleased to acknowledge the financial support from Xinxiang Medical University.
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Collect. Czech. Chem. Commun. 2011, Vol. 76, No. 12, pp. 1909–1915