Tetrahedron Letters p. 7709 - 7712 (1997)
Update date:2022-08-11
Topics:
Halm, Chris
Evarts, Jerry
Kurth, Mark J.
By tethering allyl sulfone to polystyrene (3-steps from polystyrene beads consisting of lithiation, sulfination, and allylation), trisubstituted olefins can be generated by Cα-sulfone alkylation and subsequent resin cleavage by S(N)2' nucleophilic displacement of sulfinate.
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