Chemistry of Heterocyclic Compounds p. 756 - 759 (1988)
Update date:2022-08-11
Topics:
Bulychev, Yu. N.
Preobrazhenskaya, M. N.
Chernyshev, A. I.
Esipov, S. E.
The N-alkylation of 4-chloro-5-cyano-1,2,3-triazole with methyl and ethyl orthoformate, and the dimethyl, diethyl and ethylene acetals of DMF has been examined.Methylation gives all three N-methyl isomers, whereas ethylation and hydroxyethylation gives 2-N-alkyl derivatives only.It has been shown for the first time that it is possible to use DMF ethylene acetal to obtain N-hydroxyethylazoles.The structure of the products were established by 13C NMR spectroscopy.
View Moreshanghai Tauto Biotech Co., Ltd
website:http://www.tautobiotech.com/en/index.htm
Contact:+86-21-51320588 ext. 8025
Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
Hangzhou Gangjin Chemical Co.,Ltd.
Contact:+86-571-85109780
Address:707 Zhejiang Minhang Bldg., No.290 Zhongshan North Road, Hangzhou 310003, China
Contact:021-61840961 021-61840962
Address:No.157,Zhuguang Rd, Qingpu, Shanghai, China
WUXI HONOR SHINE CHEMICAL CO.,LTD
Contact:+86-510-83593312
Address:No.1699 Huishan avenue,Huishan district,Wuxi ,Jiangsu,China,214177.(Wuxi Huishan Ecomonic Develop Zone )
Contact:+86-134-5286-9121
Address:Add: Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong,
Doi:10.1002/adsc.201300284
(2013)Doi:10.1039/c5ra26005a
(2016)Doi:10.1021/op800065q
(2008)Doi:10.1039/b805824e
(2009)Doi:10.1021/jo962310z
(1997)Doi:10.1002/chir.22150
(2013)