Organometallics
Note
Notes
Table 2. N-Formylation of Amines 1 via Copper-Catalyzed
The authors declare no competing financial interest.
Hydroboration of CO2
ACKNOWLEDGMENTS
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Support has been provided in part by the Funding Program for
Next Generation World-Leading Researchers, Green Innova-
tion and the Global COE Program “Chemistry Innovation
through Cooperation of Science and Engineering” from MEXT
of Japan.
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CONCLUSIONS
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In summary, we have developed a copper/N-heterocyclic
carbene-catalyzed hydroboration of carbon dioxide under mild
conditions to give a formic acid derivative selectively for the
first time. We have also carried out investigations to gain
insights into the catalytic cycle of this process and utilized the
hydroboration product as a formylation reagent for various
amines as well. Future studies will be directed toward the
development of more active catalyst systems for reductive
utilization of carbon dioxide.
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ASSOCIATED CONTENT
* Supporting Information
Text and figures giving experimental procedures and compound
characterization data. This material is available free of charge via
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AUTHOR INFORMATION
Corresponding Author
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(8) Mankad, N. P.; Laitar, D. S.; Sadighi, J. P. Organometallics 2004,
23, 3369.
(9) Jurkauskas, V.; Sadighi, J. P.; Buchwald, S. L. Org. Lett. 2003, 5,
2417.
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