RSC Advances
Paper
protocol reduces the agglomeration probability of the resulting 15 (a) S. Chen, J. Liu, Y. Liu, H. Su, Y. Hong, C. K. Jim,
nanoparticles. Finally, the uorescence pH sensing perfor-
mance of this new sensor (MeIm-Sal-IL) and nanosensor (MeIm-
Sal-IL-labeled SiNPs) within the pH range of 5 to 9 has been
addressed. The advantages of our new probe not only include
a large Stokes shi (ꢀ125 nm) and extreme aqueous solubility
along with simultaneous color and uorescence prole changes
R. T. Kwok, N. Zhao, W. Qin and J. W. Lam, Chem. Sci.,
2012, 3, 1804–1809; (b) Z. Yang, W. Qin, J. W. Lam,
S. Chen, H. H. Sung, I. D. Williams and B. Z. Tang, Chem.
Sci., 2013, 4, 3725–3730; (c) S. Chen, Y. Hong, Y. Liu, J. Liu,
C. W. Leung, M. Li, R. T. Kwok, E. Zhao, J. W. Lam and
Y. Yu, J. Am. Chem. Soc., 2013, 135, 4926–4929.
as a result of pH alteration, but also the probability of utilizing 16 F. Gao, L. Tang, L. Dai and L. Wang, Spectrochim. Acta, Part A,
this pH probe in an important pH range. Also, we found that the 2007, 67, 517–521.
plot of the ratio F378/F323 versus pH within the range of 5 to 9 was 17 J. L. Tan, M. X. Zhang, F. Zhang, T. T. Yang, Y. Liu, Z. B. Li
clearly linear, which covers most physiological pH values. In the and H. Zuo, Spectrochim. Acta, Part A, 2015, 140, 489–494.
future, we are looking forward to using this probe in biological 18 Y. Chen, H. Wang, L. Wan, Y. Bian and J. Jiang, J. Org. Chem.,
applications. Finally, to utilize our pH nanosensor for other 2011, 76, 3774–3781.
applications, we can change the pH application range by 19 W. Z. Yuan, P. Lu, S. Chen, J. W. Lam, Z. Wang, Y. Liu,
introducing different substituent groups into the salicylalde-
hyde skeleton, which changes the pK of the probe.
a
H. S. Kwok, Y. Ma and B. Z. Tang, Adv. Mater., 2010, 22,
2159–2163.
20 F. S. Santos, E. Ramasamy, V. Ramamurthy and
F. S. Rodembusch, Photochem. Photobiol. Sci., 2014, 13,
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