Basic information
- Name:
Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one,4,6,7,14-tetrahydro-5-methyl-
- Superlist Name:
- Protopine
- CAS No.:
130-86-9
- Molecular Structure:
![Molecular Structure of 130-86-9 (Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one,4,6,7,14-tetrahydro-5-methyl-)](http://www.lookchem.com/300w/2010/074/130-86-9.jpg)
- Formula:
- C20H19NO5
- Synonyms:
- 7,13a-Secoberbin-13a-one,7-methyl-2,3:9,10-bis(methylenedioxy)- (8CI);Protopine (6CI);Biflorine;Corydinine;Fumarine;Macleyine;Protopin;
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Chemistry
Chemical Name: Protopine
CAS No.: 130-86-9
EINECS: 204-999-6
RTECS Class: Agricultural Chemical and Pesticide
Molecular Formula: C20H19NO5
Molecular Weight: 353.37 g/mol
Density: 1.323 g/cm3
Flash Point: 284.9 °C
Boiling Point: 547.5 °C at 760 mmHg
Following is the structure of Fumarine (130-86-9):

The chemical synonymous of Fumarine (130-86-9) are 7,13a-Secoberbin-13a-one, 7-Methyl-2,3:9,10-bis(methylenedioxy)- ; 7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-C:5,6-G]azecin-15(7h)-one ; Biflorine ; Bis[1,3]Benzodioxolo[4,5-C:5',6'-G]azecin-13(5H)-one, 4,6,7,14-Tetrahydro-5-methyl- ; Corydinine ; Hypercorine ; Protopin ; Biflorin
Toxicity Data With Reference
| 1. | ipr-rat LDLo:100 mg/kg | NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),24. | ||
| 2. | ipr-mus LD50:482 mg/kg | YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. 16 (6)(1981),7. | ||
| 3. | orl-gpg LD50:237 mg/kg | THERAP Therapie. 28 (1973),767. | ||
| 4. | ipr-gpg LD50:116 mg/kg | THERAP Therapie. 28 (1973),767. |
Safety Profile
Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
Attention:
1. Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
2. Handling: All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
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