Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
GLYCIDOL |
EINECS | 209-128-3 |
CAS No. | 556-52-5 | Density | 1.179 g/cm3 |
PSA | 32.76000 | LogP | -0.62250 |
Solubility | soluble in water | Melting Point |
-54 °C |
Formula | C3H6O2 | Boiling Point | 162.358 °C at 760 mmHg |
Molecular Weight | 74.0794 | Flash Point | 81.111 °C |
Transport Information | UN 2810 6.1/PG 3 | Appearance | colourless liquid |
Safety | 53-45 | Risk Codes | 45-60-21/22-23-36/37/38-68 |
Molecular Structure | Hazard Symbols | T | |
Synonyms |
1-Propanol,2,3-epoxy- (7CI,8CI);Glycidol (6CI);Oxiranemethanol (9CI);(RS)-Glycidol;1,2-Epoxy-3-hydroxypropane;2,3-Epoxy-1-propanol;2-(Hydroxymethyl)oxirane;3-Hydroxypropylene oxide;Allyl alcohol oxide;Epihydrin alcohol;Epiol OH;Glycidyl alcohol;NSC 46096;Oxiran-2-ylmethanol;Racemic glycidol;dl-Glycidol; |
Article Data | 168 |
Conditions | Yield |
---|---|
With tert.-butylhydroperoxide; bis(acetylacetonate)oxovanadium In chlorobenzene at 80℃; for 5h; | 100% |
With sodium persulfate; water at 20℃; for 12h; Reagent/catalyst; | 100% |
With tetrabutylphosphonium peroxotantalate; dihydrogen peroxide In water at 0℃; for 5.5h; Schlenk technique; chemoselective reaction; | 100% |
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol; water at -5 - 15℃; for 6h; Large scale; | 98.5% |
With sodium hydroxide In water at 18 - 36℃; under 18.7519 Torr; Temperature; Pressure; Concentration; Industrial scale; | 97.92% |
With sodium methylate In methanol at 0 - 15℃; under 2100.21 - 2325.23 Torr; for 0.833333h; Pressure; Temperature; | 93.76% |
Conditions | Yield |
---|---|
With zinc(II) nitrate; 1-butyl-3-methylimidazolium nitrate at 175℃; under 20.027 Torr; for 2.5h; | 98.2% |
With zinc-lanthanum mixed oxides at 180℃; under 375.038 Torr; Reagent/catalyst; | 76.22% |
With sodium sulfate at 140 - 180℃; for 3h; Green chemistry; | 33% |
Conditions | Yield |
---|---|
With lithium tetrafluoroborate In dichloromethane at 20℃; for 0.25h; deprotection; | A 92% B n/a |
glycerol
carbonic acid dimethyl ester
A
4-hydroxymethyl-1,3-dioxolan-2-one
B
oxiranyl-methanol
Conditions | Yield |
---|---|
With 30 wt.% KF/γ-Al2O3 at 80℃; for 1.5h; Catalytic behavior; Reagent/catalyst; | A 91.3% B n/a |
With fluorinated Mg-Al hydrotalcite derived basic catalyst at 110℃; for 3h; Reagent/catalyst; | A 80.5% B 10.8% |
With Mg/Zr/Sr mixed oxide at 90℃; for 1.5h; Catalytic behavior; Temperature; Concentration; Reagent/catalyst; | A 56% B 40% |
2-fluoroethanol
2-fluoro-2-phenylethanol
A
trans-3-chloroallyl 2,3-epoxypropyl ether
B
2-(2-Fluoro-2-phenyl-ethoxymethyl)-oxirane
C
oxiranyl-methanol
Conditions | Yield |
---|---|
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate at 25℃; for 24h; Yields of byproduct given; | A n/a B 75% C n/a |
2-fluoroethanol
trans-2-fluorocyclohexanol
2-((1S,2S)-2-Fluoro-cyclohexyloxymethyl)-oxirane
B
trans-3-chloroallyl 2,3-epoxypropyl ether
C
oxiranyl-methanol
Conditions | Yield |
---|---|
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate at 25℃; for 24h; Yields of byproduct given; | A 65% B n/a C n/a |
4-hydroxymethyl-1,3-dioxolan-2-one
A
2,5-Bis(hydroxymethyl)-1,4-dioxane
C
3-(oxrian-2-yloxy)propane-1,2-diol
D
oxiranyl-methanol
Conditions | Yield |
---|---|
With sodium chloride at 175℃; under 20.027 Torr; for 0.75h; | A n/a B n/a C n/a D 62% |
glycerol
A
1,3-dioxolane-4-methanol
B
glycerol formal
C
glycolic Acid
D
ethyl 2-hydroxyacetate
E
diglycerol
F
oxiranyl-methanol
G
hydroxy-2-propanone
H
acrolein
Conditions | Yield |
---|---|
With pretreated aluminium vanadium phosphate In water at 280℃; under 760.051 Torr; Catalytic behavior; Activation energy; Reagent/catalyst; Temperature; | A n/a B n/a C n/a D n/a E n/a F n/a G n/a H 62% |
glycerol
carbonic acid dimethyl ester
A
4-hydroxymethyl-1,3-dioxolan-2-one
B
methyl ((2-oxo-1,3-dioxolan-4-yl)methyl)carbonate
C
oxiranyl-methanol
Conditions | Yield |
---|---|
With potassium fluoride at 80℃; for 1.5h; Catalytic behavior; Reagent/catalyst; | A 58.4% B n/a C n/a |
With tetrabutylammomium bromide at 160℃; under 8250.83 Torr; for 0.05h; Flow reactor; |
1.Glycidol is used as a stabilizer for natural oils and vinyl polymers and as a demulsifier.
2.Used in surface coatings, pharmaceuticals, chemical synthesis, and as a gelation agent in solid propellants etc.
3.As a chemical intermediate in the synthesis of glycerol, esters,amines and glycidyl ethers,.
1. | skn-rbt 558 mg/3D MOD | AMIHAB AMA Archives of Industrial Health. 14 (1956),250. | ||
2. | mmo-klp 200 µmol/L | MUREAV Mutation Research. 89 (1981),269. | ||
3. | cyt-hmn:lym 400 µmol/L | MUREAV Mutation Research. 91 (1981),243. | ||
4. | orl-rat LD50:420 mg/kg | FCTXAV Food and Cosmetics Toxicology. 19 (1981),347. | ||
5. | ihl-rat LC50:580 ppm/8H | AMIHAB AMA Archives of Industrial Health. 14 (1956),250. | ||
6. | ipr-rat LD50:200 mg/kg | FCTXAV Food and Cosmetics Toxicology. 19 (1981),347. | ||
7. | orl-mus LD50:431 mg/kg | GTPZAB Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 24 (3)(1980),42. | ||
8. | ihl-mus LC50:450 ppm/4H | AMIHAB AMA Archives of Industrial Health. 14 (1956),250. | ||
9. | ipr-mus LDLo:500 mg/kg | PSEBAA Proceedings of the Society for Experimental Biology and Medicine. 35 (1936),98. | ||
10. | skn-rbt LD50:1980 mg/kg | AMIHAB AMA Archives of Industrial Health. 14 (1956),250. |