Basic information
- Name:
18,19-Dinorpregna-4,9,11-trien-20-yn-3-one,13-ethyl-17-hydroxy-, (17a)-
- Superlist Name:
- Gestrinone
- CAS No.:
16320-04-0
- Molecular Structure:
- Formula:
- C21H24O2
- Molecular Weight:
- 308.45
- Deleted CAS:
- 40542-65-2
- Synonyms:
- 18,19-Dinor-17a-pregna-4,9,11-trien-20-yn-3-one,13-ethyl-17-hydroxy- (8CI);13-Ethyl-17a-ethynyl-17b-hydroxygona-4,9,11-trien-3-one;Dimetriose;Dimetrose;Nemestran;R 2323;RU 2323;Tridomose;
- Density:
- 1.18 g/cm3
- Melting Point:
- 150-152 °C
- Boiling Point:
- 507.6 °C at 760mmHg
- Flash Point:
- 214.9 °C
- Appearance:
- Light yellow solid
Famous Chemical Enterprises
-
Livzon -
Total -
Shell -
Dupont -
Exxonmobil -
Akzonobel -
Basf -
Bayer -
BP
Please post your buying leads,so that our qualified suppliers will soon
contact you!
*Required Fields
Chemistry
IUPAC Name: (8S,13S,14S,17R)-13-Ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
The MF of Gestrinone (CAS NO.16320-04-0) is C21H24O2.
The MW of Gestrinone (CAS NO.16320-04-0) is 308.41.
Synonyms of Gestrinone (CAS NO.16320-04-0): (17a)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,9,11-trien-20-yn-3-one ; 13b-Ethyl-17a-ethynyl-D4,9,11-gonatriene-17b-ol-3-one ; 18,19-Dinorpregna-4,9,11-trien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17alpha)-
Product Categories: Active Pharmaceutical Ingredients;Hormone
Index of Refraction: 1.606
Density: 1.18 g/ml
Flash Point: 214.9 °C
Boiling Point: 507.6 °C
Melting Point: 154 °C
Uses
Gestrinone (CAS NO.16320-04-0) is progesterone used for endometriosis.
Production
Raw materials: Nitrogen-->Cyclohexane-->Tetrahydro pyrrole-->Pyruvic acid-->2-N-Butoxyethyl methacrylate-->Acetylacetone-->Magnesium silicate-->Estradiene dione-3-keta
Toxicity Data With Reference
| 1. | orl-rat LDLo:1 g/kg | YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 16 (1988),701. | ||
| 2. | ipr-rat LDLo:1 g/kg | YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 16 (1988),701. | ||
| 3. | ipr-mus LDLo:1 g/kg | YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 16 (1988),701. |
Safety Profile
Human reproductive effects by ingestion, implant or intravaginal routes: menstrual cycle changes and disorders, and changes in female fertility. An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes.