Basic information
- Name:
Glipizide
- CAS No.:
29094-61-9
- Molecular Structure:
- Formula:
- C21H27N5O4S
- Molecular Weight:
- 445.53
- Deleted CAS:
- 38777-27-4|29094-66-4|172964-66-8
- Synonyms:
- Glucotrol;Glydiazinamide;Prestwick_242;N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methyl-pyrazine-2-carboxamide;Pyrazinecarboxamide,N-[2-[4-[[[(cyclohexylamino) carbonyl]amino]sulfonyl]phenyl]- ethyl]-5-methyl-;TK 1320;Glucotrol (TN);(Glipizide);
- EINECS:
- 249-427-6
- Density:
- 1.34 g/cm3
- Melting Point:
- 208-209 °C
- Solubility:
- methanol: 1.9 mg/mL
- Appearance:
- crystalline solid
- Hazard Symbols:
Xi,
Xn- Risk Codes:
- 21-36/38-46-62-63
- Safety Description:
- 24/25-53-36/37-26-25 Details
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Chemistry
Molecular Structure of Glipizide (CAS NO.29094-61-9):
IUPAC Name:N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methylpyrazine-2-carboxamide
Molecular Formula: C21H27N5O4S
Molecular Weight: 445.535180 g/mol
Appearance: white solid
Melting Point: 208-209°C
H bond acceptors: 9
H bond donors: 3
Freely Rotating Bonds: 6
Polar Surface Area: 112.16Å2
Index of Refraction: 1.615
Molar Refractivity: 115.92 cm3
Molar Volume: 331.8 cm3
Surface Tension: 66.8 dyne/cm
Density: 1.34 g/cm3
Solubility: methanol 1.9 mg/mL
Categories: Intermediates & Fine Chemicals; Pharmaceuticals; API's; Potassium channel
Safety Profile
Safety Information of Glipizide (CAS NO.29094-61-9):
Hazard Codes: 
Xn,
Xi
Risk Statements: 21-36/38-46-62-63
21:Harmful in contact with skin
36/38:Irritating to eyes and skin
46:May cause heritable genetic damage
62:Possible risk of impaired fertility
63:Possible risk of harm to the unborn child
Safety Statements: 24/25-53-36/37-26-25
24/25:Avoid contact with skin and eyes
53:Avoid exposure - obtain special instruction before use
36/37:Wear suitable protective clothing and gloves
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
25:Avoid contact with eyes
WGK Germany: 3
RTECS: YS7640000
F: 10
Specification
Glipizide , with CAS number of 29094-61-9, can be called 2-pyrazinecarboxamide, N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl- ; N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-2-pyrazinecarboxamide ; Pyrazinecarboxamide, N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl- . Glipizide (CAS NO.29094-61-9) is an oral medium-to-long acting anti-diabetic drug.