9-Phenanthrenemethanol,1,3-dichloro-alpha-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)-,hydrochloride (1:1)

The IUPAC Name of Halofantrine hydrochloride is 3-(Dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol hydrochloride . With the CAS registry number 36167-63-2, it is also named as 1,3-Dichloro-alpha-[2-(dibutylamino)ethyl]-6- (trifluoromethyl)-9-phenathrenemethanol hydrochloride and (+-)-Halofantrine hydrochloride . In addition, it belongs to classification code such as Anti-Infective Agents, Antimalarial and Antimalarials, it is storage at 2-8 °C.

This product is used in treatment of mild to moderate acute malaria. It is an antimalarial drug available as tablets containing 250 mg of halofantrine hydrochloride (equivalent to 233 mg of the free base) for oral administration. And this drug, a white to off-white crystalline compound, is practically insoluble in water. 

The other characteristics of this product can be summarized as: (1)H bond acceptors: 2; (2)H bond donors: 1; (3)Freely Rotating Bonds: 11; (4)Flash Point: 313.3 °C; (5)Enthalpy of Vaporization: 93.17 kJ/mol; (6)Boiling Point: 594.3 °C at 760 mmHg; (7)Vapour Pressure: 5.67E-15 mmHg at 25 °C (8) EINECS: 252-895-4.

When you are using this chemical, please be cautious about it as the following: It is moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by ingestion: nausea or vomiting and other gastrointestinal effects, and it is an experimental teratogen. Moreover, it has experimental reproductive effects. When heated to decomposition it emits toxic fumes of F^-, NO_x, and HCl. The toxicity of Halofantrine hydrochloride as follows: