Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Hydroxyprogesterone

Related Products

Hot Products

Name

Hydroxyprogesterone

EINECS 200-699-4
CAS No. 68-96-2 Density 1.15 g/cm3
PSA 54.37000 LogP 3.69430
Solubility 5.056mg/L(20 oC) Melting Point 276 °C
Formula C21H20O3 Boiling Point 482.9 °C at 760 mmHg
Molecular Weight 330.467 Flash Point 259.9 °C
Transport Information N/A Appearance White solid
Safety 53-22-36/37/39-45 Risk Codes 61
Molecular Structure Molecular Structure of 68-96-2 (Hydroxyprogesterone) Hazard Symbols Toxic
Synonyms

17-Hydroxypregn-4-ene-3,20-dione;17-Hydroxyprogesterone;17a-Hydroxylutin;17a-Hydroxypregn-4-ene-3,20-dione;17a-Hydroxyprogesterone;Gestageno;Gestageno Gador;Pregn-4-en-17a-ol-3,20-dione;Prodix;D4-Pregnen-17a-ol-3,20-dione;

Article Data 86

Hydroxyprogesterone Synthetic route

20380-16-9

17α-hydroxy-21-chloro-4-pregnene-3,20-dione

68-96-2

17-hydroxyprogesterone

Conditions
ConditionsYield
With acetic acid; zinc100%
With titanium(III) sulphate; sulfuric acid; ammonia In methanol for 10h;83%
1202062-99-4

cyclic-3-(1,2-ethanediylmercapto)-17α-hydroxypregn-4-en-20-one

68-96-2

17-hydroxyprogesterone

Conditions
ConditionsYield
With water; calcium carbonate; methyl iodide In ethanol for 20h; Heating; Inert atmosphere;100%
4470-79-5

21-Iodo-17α-hydroxypregn-4-en-3,20-dione

68-96-2

17-hydroxyprogesterone

Conditions
ConditionsYield
With mercaptoacetic acid In formamide for 0.25h; Ambient temperature;97.7%

C23H34NO3(1-)*Zn(2+)*Br(1-)

68-96-2

17-hydroxyprogesterone

Conditions
ConditionsYield
With hydrogenchloride In methanol; water at 40℃; for 4h; pH=1.5 - 2; Temperature; Reagent/catalyst;97.4%
83509-38-0

17β-Ethynyl-17α-hydroxyandrost-4-en-3-one

68-96-2

17-hydroxyprogesterone

Conditions
ConditionsYield
With sulfuric acid; mercury(II) sulfate In water; acetone at 50 - 55℃; for 6h; Temperature;86%

C22H31NO3

544-97-8

dimethyl zinc(II)

68-96-2

17-hydroxyprogesterone

Conditions
ConditionsYield
Stage #1: C22H31NO3; dimethyl zinc(II) With lithium chloride In toluene at 60 - 65℃;
Stage #2: With hydrogenchloride In water at 55 - 60℃; Solvent; Reagent/catalyst;
85.2%
1096-38-4

16-dehydroprogesterone

68-96-2

17-hydroxyprogesterone

Conditions
ConditionsYield
Stage #1: 16-dehydroprogesterone With phenylsilane; oxygen; isopropyl alcohol; Mn(dpm)3 In 1,2-dichloro-ethane at 0 - 25℃;
Stage #2: With triethyl phosphite In 1,2-dichloro-ethane
85%
Multi-step reaction with 2 steps
1: 79 percent / RhCl(PPh3)3
2: mCPBA / RhCl(PPh3)3 / CH2Cl2
View Scheme
1096-38-4

16-dehydroprogesterone

Mn(dpm)3

Mn(dpm)3

107-06-2

1,2-dichloro-ethane

68-96-2

17-hydroxyprogesterone

Conditions
ConditionsYield
In isopropyl alcohol85%
68-96-2

17-hydroxyprogesterone

Conditions
ConditionsYield
With water; sodium hydroxide In methanol for 1h; Reflux;83.3%
With potassium hydroxide
4470-79-5

21-Iodo-17α-hydroxypregn-4-en-3,20-dione

68-11-1

mercaptoacetic acid

A

68-96-2

17-hydroxyprogesterone

B

114967-85-0

(17α-Hydroxy-4-pregnene-3,20-dion-21-yl-21-thio)acetic acid

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 80℃;A 71.8%
B 24.6%

Hydroxyprogesterone Chemical Properties

Product Name: Hydroxyprogesterone (CAS NO.68-96-2)

Molecular Formula: C21H30O3
Molecular Weight: 330.46g/mol
EINECS: 200-699-4
Appearance: White Solid
Melting Point: 276°C
Boiling point: 482.9 °C at 760 mmHg
Flash Point: 259.9 °C
Density: 1.15 g/cm3
Refractive index: 90 ° (C=1, CHCl3)
Surface Tension: 46.5 dyne/cm
Enthalpy of Vaporization: 86.18 kJ/mol
Vapour Pressure: 2.37E-11 mmHg at 25°C
XLogP3-AA: 3.2
H-Bond Donor: 1
H-Bond Acceptor: 3
Structure Descriptors of Hydroxyprogesterone (CAS NO.68-96-2):
  IUPAC Name: (8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
  Canonical SMILES: CC(=O)C1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
  Isomeric SMILES: CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
  InChI: InChI=1S/C21H30O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h12,16-18,24H,4-11H2,1-3H3/t16-,17+,18+,19+,20+,21+/m1/s1 
  InChIKey: DBPWSSGDRRHUNT-CEGNMAFCSA-N
Product Categories: Steroids; Biochemistry; Hydroxyketosteroids; Intermediates & Fine Chemicals; Pharmaceuticals 

Hydroxyprogesterone Safety Profile

Safety Information of Hydroxyprogesterone (CAS NO.68-96-2):
Hazard Codes: TToxic
Risk Statements: 61  
R61:May cause harm to the unborn child.
Safety Statements: 53-22-36/37/39-45
S52:Not recommended for interior use on large surface areas. 
S22:Do not breathe dust. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
RTECS: TU5060000
Hazardous Substances Data: 68-96-2(Hazardous Substances Data) 

Hydroxyprogesterone Specification

 Hydroxyprogesterone , its CAS NO. is 68-96-2, the synonyms are 17-Hydroxypregn-4-ene-3,20-dione ; 17-Hydroxyprogesterone ; Gestageno gador ; HSDB 3343 ; Hydroxyprogesteronum ; Idrossiprogesterone ; NSC 15468 ; Oxiprogesteronum ; Pregn-4-ene-3,20-dione, 17-hydroxy- ; Proluton ; Setaderm ; alpha Hydroxy progesterone ; delta(4)-Pregnene-17alpha-ol-3,20-dione . 

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 68-96-2